Olinvacimab
Olinvacimab Basic information
- Product Name:
- Olinvacimab
- Synonyms:
-
- Olinvacimab
- Tanibirumab
- Research Grade Olinvacimab (DHE16602)
- Research Grade Tanibirumab (DHE16604)
- Research Grade Olinvacimab
- Research Grade Tanibirumab
- Olinvacimab (anti-VEGFR2)
- CAS:
- 2095504-49-5
- MW:
- 0
- Mol File:
- Mol File
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Olinvacimab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Olinvacimab Usage And Synthesis
Uses
Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer[1].
in vivo
Olinvacimab (100 ng; s.c., once) inhibits angiogenesis in vivo[1].
| Animal Model: | Matrigel-implanted nude mice model[1] |
| Dosage: | 100 ng |
| Administration: | Subcutaneous injection; 100 ng, once |
| Result: | Inhibited the neovascularization induced by hVEGF165. |
References
[1] Lee WS, et al. TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis. MAbs. 2015;7(5):957-68. DOI:10.1080/19420862.2015.1045168
OlinvacimabSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
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- 021-61312847; 18021002903
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ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Guangzhou Hongyuan Chemical Co.,Ltd
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Wuhan Chemstan Biotechnology Co., Ltd.
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- 027-65317797 15926423062
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TargetMol Chemicals Inc.
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