N,N'-Dimorpholinomethane Chemical Properties

Boiling point:

122-124°C 12mm

Density 

1,04 g/cm³

refractive index 

1.4790 (estimate)

storage temp. 

2-8°C

pka

6.91±0.10(Predicted)

Appearance

Colorless to light yellow Liquid

Water Solubility 

Soluble in water.

InChI

InChI=1S/C9H18N2O2/c1-5-12-6-2-10(1)9-11-3-7-13-8-4-11/h1-9H2

InChIKey

MIFZZKZNMWTHJK-UHFFFAOYSA-N

SMILES

C(N1CCOCC1)N1CCOCC1

CAS DataBase Reference

5625-90-1(CAS DataBase Reference)

EPA Substance Registry System

Morpholine, 4,4'-methylenebis- (5625-90-1)

Safety Information

Hazard Codes 

Xi,F

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HazardClass 

IRRITANT, FLAMMABLE

N,N'-Dimorpholinomethane Usage And Synthesis

Uses

It is employed as intermediate for pharmaceutical.

Synthesis

In a 500 mL four-necked flask equipped with an electric stirrer and a condenser tube, the solvent chlorobenzene, 174 g (2 mol) morpholine and 0.348 g 5% aqueous dodecyldimethylbenzylammonium hydroxide were added sequentially, and 81.08 g (1 mol) of 37% formaldehyde solution was slowly put into the four-necked flask under an ice-water bath, and the temperature was not exceeded at 70 ?? during the feeding process, and the temperature was kept at 70 ?? for 3 hrs after finishing feeding. It was held for 3 hours, then cooled to room temperature and distilled under reduced pressure to remove the solvent chlorobenzene and water to obtain the target product N,N'-methylenebismorpholine 189.23 g in 98.01% yield.

N,N'-Dimorpholinomethane(5625-90-1)Related Product Information

• Moroxydine hydrochloride
• Moroxydine
• Dimethomorph
• N-Formylmorpholine
• AURORA KA-2293
• AURORA KA-3562
• AURORA KA-4848
• AURORA KA-2295
• 1,1-BIS(MORPHOLINO)ETHYLENE
• AURORA KA-2299
• N,N'-Dimorpholinomethane