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Isochlorogenic Acid B

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Isochlorogenic Acid B Basic information

Product Name:
Isochlorogenic Acid B
Synonyms:
  • Isochlorogenic acid B, froM Lonicera japonica
  • 3,4-Dicaffeoylquinic acid
  • Isochlorogenic acid B
  • Isochlorogenic acid B,3,4-Dicaffeoylquinic acid
  • (1S)-1α,5α-Dihydroxy-3β,4α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β-cyclohexanecarboxylic acid
  • (1S)-4β,5α-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β,3β-dihydroxycyclohexanecarboxylic acid
  • 1β,3β-Dihydroxy-4β,5α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1α-cyclohexanecarboxylic acid
  • ISOCHLOROGENIC ACID B(RG)
CAS:
14534-61-3
MF:
C25H24O12
MW:
516.45
Product Categories:
  • The group of Chlorogenic acid
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
14534-61-3.mol
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Isochlorogenic Acid B Chemical Properties

Melting point:
>117°C (sub.)
Boiling point:
810.8±65.0 °C(Predicted)
Density 
1?+-.0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Methanol (Slightly)
form 
Solid
pka
3.70±0.50(Predicted)
color 
Off-White to Light Yellow
InChIKey
UFCLZKMFXSILNL-BBLPPJRLSA-N
SMILES
[C@]1(O)(C(O)=O)C[C@@H](O)[C@@H](OC(=O)C=CC2=CC=C(O)C(O)=C2)[C@H](OC(=O)C=CC2=CC=C(O)C(O)=C2)C1
LogP
0.890 (est)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29189900
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Isochlorogenic Acid B Usage And Synthesis

Chemical Properties

Colorless crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from honeysuckle, honeysuckle, and eucommia.

Uses

Isochlorgenic Acid is shown to provide antioxidant and DNA-protective activities.

Definition

ChEBI: Isochlorogenic acid b is a quinic acid.

Biological Activity

3,4-Di-O-caffeoylquinic acid, along with 3,5-dicaffeoylquinic acid and luteolin-7-O-glucoside, is a component of the medicinal herb Youngia japonica. It has known antiviral activity and along with 3,5,-dicaffeoylquinic acid, shows activity against respiratory syncyntial virus (RSV). 3,4-COQ elicits antioxidant effects which mediate its neuroprotective effects against in vitro retinal damage. It also exerts cytoprotective effects against oxidative damage in bone marrow-derived mesenchymal stem cells (bmMSCs).

target

PDE-5

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