Methyl 5-chloroanthranilate Chemical Properties

Melting point:

66-68 °C (lit.)

Boiling point:

168-170 °C/22 mmHg (lit.)

Density 

1.2797 (rough estimate)

refractive index 

1.5560 (estimate)

Flash point:

168-170°C/1mm

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

soluble in Methanol

form 

Crystals or Crystal Powder

pka

1.76±0.10(Predicted)

color 

Cream to beige-brown

BRN 

1072894

InChI

InChI=1S/C8H8ClNO2/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4H,10H2,1H3

InChIKey

IGHVUURTQGBABT-UHFFFAOYSA-N

SMILES

C(OC)(=O)C1=CC(Cl)=CC=C1N

CAS DataBase Reference

5202-89-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzoic acid, 2-amino-5-chloro-, methyl ester(5202-89-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29224999

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Methyl 5-chloroanthranilate Usage And Synthesis

Chemical Properties

Tan powder

Uses

Methyl 2-Amino-5-chlorobenzoate is a building block that has been used as a reactant for the preparation of bacterial RNA polymerase inhibitors.

General Description

Methyl 2-amino-5-chlorobenzoate is a useful pharmaceutical intermediate. Crystal structure of methyl 2-amino-5-chlorobenzoate was studied.

References

[1] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 8, p. 1743 - 1754
[2] Patent: WO2012/46244, 2012, A1. Location in patent: Page/Page column 6
[3] Patent: US2013/190490, 2013, A1. Location in patent: Paragraph 0048; 0049

Methyl 5-chloroanthranilate(5202-89-1)Related Product Information

• 2-Amino-5-chlorobenzamide
• Methylparaben
• Methyl anthranilate
• Methyl acetate
• Methyl 2-bromobenzoate
• Kresoxim-methyl
• METHYL THIOPHENE-2-CARBOXYLATE
• Trimethoxymethane
• Bensulfuron methyl
• Methyl benzoate
• 2-Amino-5-chlorobenzoic acid
• Methyl formate
• Methyl acrylate
• 2-Amino-4-methylbenzoic acid methyl ester
• METHYL 2-AMINO-3-TRIFLUOROMETHYLBENZOATE
• METHYL 2-AMINO-5-BROMOBENZOATE
• Thiophanate-methyl
• METHYL 2-BROMO-4,5-DIFLUOROBENZOATE