irisolidone Chemical Properties

Melting point:

190-191 °C

Boiling point:

565.5±50.0 °C(Predicted)

Density 

1.402±0.06 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

Chloroform (Slightly), DMSO (Slightly)

form 

Solid

pka

6.48±0.20(Predicted)

color 

Off-White to Pale Yellow

irisolidone Usage And Synthesis

Description

Irisolidone is a hydrolyzed product of kudzurin. Studies have shown that it can significantly dilate coronary arteries, cerebral arteries and peripheral blood vessels and microvessels, and can reduce vascular resistance, cholesterol and blood viscosity.

Chemical Properties

Light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from kudzu.

Uses

Irisolidone has anti-inflammatory, antioxidant, antibacterial, anti-tumor, estrogen-like effects, and protects liver damage caused by alcoholism.

Definition

ChEBI: Irisolidone is a member of 4'-methoxyisoflavones.

Biological Activity

Irisolidone is the main isoflavone in pueraria. Irisolidone has strong hepatoprotective activity. It has a highly effective blocking effect on the anion channel VRAC.

in vitro

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