ChemicalBook > Product Catalog > Analytical Chemistry > Analysis reagents > Ion chromatography reagents > Ufiprazole
Ufiprazole
Ufiprazole Basic information
- Product Name:
- Ufiprazole
- Synonyms:
-
- 5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE
- 5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLMERCAPTOBENZIMIDAZOLE
- 5-METHOXY-2-[[(3,5-DIMETHYL-4-METHOXY PYRIDINYL)-METHYL]THIO]-1H-BENZIMIDAZOLE
- 2-[(4-METHOXYETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLTHIO]-5-METHOXYBENZIMIDAZOLE
- 2-{[(3,5-dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1h-benzimidazole
- OMEPRAZOLE SULPHIDE
- H 168/22
- ufiprazole
- CAS:
- 73590-85-9
- MF:
- C17H19N3O2S
- MW:
- 329.42
- EINECS:
- 615-997-3
- Product Categories:
-
- zjh
- Inhibitors
- (intermediate of lamivudine)
- Intermediates & Fine Chemicals
- Metabolites
- Pharmaceuticals
- Various Metabolites and Impurities
- 73590-85-9
- Mol File:
- 73590-85-9.mol
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Ufiprazole Chemical Properties
- Melting point:
- 122.0 to 126.0 °C
- Boiling point:
- 539.7±60.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 9.81±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- λmax
- 307nm(MeOH)(lit.)
- InChI
- InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
- InChIKey
- XURCIPRUUASYLR-UHFFFAOYSA-N
- SMILES
- C1(SCC2=NC=C(C)C(OC)=C2C)NC2=CC(OC)=CC=C2N=1
- CAS DataBase Reference
- 73590-85-9(CAS DataBase Reference)
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Ufiprazole Usage And Synthesis
Synthesis
Ufiprazole can be synthesized by the condensation reaction of 2-mercapto-5-methoxybenzimidazole and 2-chloromethyl-4-methoxy-3,5-lutidine.
Description
Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole . As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 μM).
Uses
Omeprazole Sulfide (Esomeprazol EP Impurity C(Omeprazole EP Impurity C)) is a metabolite of Omeprazole.
Definition
ChEBI: Omeprazole sulfide is a member of benzimidazoles.
Biological Activity
Ufiprazole (Omeprazole sulfide) is an intermediate in the production of gastric proton pump inhibitors omeprazole and esomeprazole.
UfiprazoleSupplier
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Ufiprazole(73590-85-9)Related Product Information
- 3,5-Dimethyl-4-methoxy-2-pyridinemethanol
- Omeprazole
- OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS)
- Esomeprazole Impurity 3
- (S)-4-Desmethoxy-4-chloro Omeprazole
- 4-Hydroxy Omeprazole
- Omeprazole EP Impurity F
- Omeprazole Sulfone N-Oxide
- EsoMeprazole related substance H431/41
- 2-Pyridinemethanol, 4-hydroxy-3,5-dimethyl- (9CI)
- 5-METHOXY-2-[(3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE
- 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
- Omeprazole EP Impurity G
- Ondansetron EP Impurity H
- ammonium 1-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylate
- OMEPRAZOLE IMP. C (EP): 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL]SULPHANYL]-1H-BENZIMIDAZOLE (UFIPRAZOLE) MM STANDARD
- omeprazole acid
- Omeprazole Impurity (2-[[(5-hydroxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-3,5-dimethy-l-4(1H)-pyridone)