6-AMINOCHRYSENE
6-AMINOCHRYSENE Basic information
- Product Name:
- 6-AMINOCHRYSENE
- Synonyms:
-
- ADCA
- 6-Amc
- Chrysenex
- Chrysonex
- 6-CHRYSENAMINE
- 6-AMINOCHRYSENE
- AMINOCHRYSENE
- AMINOCHRYSENE, 6-
- CAS:
- 2642-98-0
- MF:
- C18H13N
- MW:
- 243.3
- EINECS:
- 220-149-7
- Mol File:
- 2642-98-0.mol
6-AMINOCHRYSENE Chemical Properties
- Melting point:
- 209-211 °C(lit.)
- Boiling point:
- 376.18°C (rough estimate)
- Density
- 0.8933 (rough estimate)
- refractive index
- 1.4500 (estimate)
- storage temp.
- 2-8°C
- solubility
- Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 4.32±0.30(Predicted)
- color
- Yellow to Brown
- Water Solubility
- 155ug/L(24 ºC)
- Merck
- 13,2275
- CAS DataBase Reference
- 2642-98-0(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 45-36/37/39-26
- WGK Germany
- 3
- RTECS
- GC0500000
- HS Code
- 29214900
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
6-AMINOCHRYSENE Usage And Synthesis
Chemical Properties
ORANGE TO BROWN CRYSTALLINE POWDER
Uses
Produces tumors in mice.
Uses
6-Aminochrysene is a potent inhibitor of transferase activity. Also, it is used for the synthesis of diarylthiourea analogs as novel anti-cancer agents.
Definition
ChEBI: 6-chrysenamine is a carbopolycyclic compound.
in vivo
6-Aminochrysene is an inhibitor of the growth of several solid experimental tumours in vivo and has a cancerostatic effect on human breast cancer[1]. Long term topical skin application of 6-Aminochrysene to mice induces development of benign skin tumors after 3 months and of skin malignancies after 7 months. Female mice respond earlier than males. Induction of skin tumors is more rapid when 6-Aminochrysene is applied ventrally instead of dorsally. Urinary excretion is about twice as high after skin application than after oral administration[2].
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6-AMINOCHRYSENE(2642-98-0)Related Product Information
- 6-AMINOCHRYSENE
- 6-NITROCHRYSENE
- 7-Amino-3-methyl-3-cephem-4-carboxylic acid
- 7-Aminodesacetoxycephalosporanic acid
- Chrysene
- 6-NITROCHRYSENE-D11
- 6-NITROBENZ(A)PYRENE
- 2-AMINOCHRYSENE
- N-hydroxy-6-aminochrysene
- TRANS-1,2-DIHYDROXY-1,2-DIHYDRO-6-AMINOCHRYSENE
- 6-NITROANTHANTHRENE
- 6-CHRYSENYLISOTHIOCYANATE
- 6-BENZO[A]PYRENYLISOTHIOCYANATE
- CHRYSEN-6-YL-HYDRAZINE
- 12-Aminobenzo(a)pyrene
- 6-nitrosobenzo(a)pyrene
- 3,6-dinitrobenzo(a)pyrene
- CHRYSENE, 5-METHYL-6-NITRO-