Basic information Safety Supplier Related

7-Amino-3-methyl-3-cephem-4-carboxylic acid

Basic information Safety Supplier Related

7-Amino-3-methyl-3-cephem-4-carboxylic acid Basic information

Product Name:
7-Amino-3-methyl-3-cephem-4-carboxylic acid
Synonyms:
  • Cefazedone Impurity 13
  • Cefadroxil Impurity 8(Cefadroxil EP Impurity B)
  • Cephalexin EP Impurity B (Cephalexin Impurity B, 7-ADCA)
  • Cefadroxil EP Impurity B
  • Cefadroxil Related Compound B (25 mg) ((6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid)
  • Cefalexin EP Impurity B
  • Cefadroxil EP Impurity B (Cephalexin Impurity B, 7-ADCA)
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-aMino-3-Methyl-8-oxo-, (6R,7R)-
CAS:
22252-43-3
MF:
C8H10N2O3S
MW:
214.24
EINECS:
244-870-1
Product Categories:
  • Various Metabolites and Impurities
  • Antibiotics for Research and Experimental Use
  • beta-Lactams (Antibiotics for Research and Experimental Use)
  • Biochemistry
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • LFQ
Mol File:
22252-43-3.mol
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7-Amino-3-methyl-3-cephem-4-carboxylic acid Chemical Properties

Melting point:
234°C (dec.)
Boiling point:
517.6±50.0 °C(Predicted)
Density 
1.59±0.1 g/cm3(Predicted)
vapor pressure 
0Pa at 20℃
refractive index 
104 ° (C=1, 1mol/L HCl)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
3.04±0.50(Predicted)
form 
powder
color 
White to Orange to Green
Water Solubility 
Soluble in water (partly), 1M ammonium hydroxide (50 mg/ml), and DMSO (Sparingly).
BRN 
5273616
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
-3.8--2.8 at 20℃ and pH3.6-7
CAS DataBase Reference
22252-43-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
42/43-36/37/38-20/21/22
Safety Statements 
36-26
WGK Germany 
3
HS Code 
2941901010
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7-Amino-3-methyl-3-cephem-4-carboxylic acid Usage And Synthesis

Chemical Properties

Off-White Powder

Uses

A metabolite of Cephalexin (C256800).

Uses

7-Aminodesacetoxycephalosporanic acid is the Cephalexin metabolite. It is a Potent inhibitor of bacterial cell-wall enzyme. It is used in the synthesis of cephalosporins and for bioconversion studies.

Definition

ChEBI: A cephem monocarboxylic acid derivative having a structure based on cephalosporanic acid, deacetoxylated and carrying a 7beta-amino group.

7-Amino-3-methyl-3-cephem-4-carboxylic acid Preparation Products And Raw materials

Preparation Products

7-Amino-3-methyl-3-cephem-4-carboxylic acidSupplier

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