7-Amino-3-methyl-3-cephem-4-carboxylic acid
7-Amino-3-methyl-3-cephem-4-carboxylic acid Basic information
- Product Name:
- 7-Amino-3-methyl-3-cephem-4-carboxylic acid
- Synonyms:
-
- Cefazedone Impurity 13
- Cefadroxil Impurity 8（Cefadroxil EP Impurity B）
- Cephalexin EP Impurity B (Cephalexin Impurity B, 7-ADCA)
- Cefadroxil EP Impurity B
- Cefadroxil Related Compound B (25 mg) ((6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid)
- Cefalexin EP Impurity B
- Cefadroxil EP Impurity B (Cephalexin Impurity B, 7-ADCA)
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-aMino-3-Methyl-8-oxo-, (6R,7R)-
- CAS:
- 22252-43-3
- MF:
- C8H10N2O3S
- MW:
- 214.24
- EINECS:
- 244-870-1
- Product Categories:
-
- Various Metabolites and Impurities
- Antibiotics for Research and Experimental Use
- beta-Lactams (Antibiotics for Research and Experimental Use)
- Biochemistry
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- LFQ
- Mol File:
- 22252-43-3.mol
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7-Amino-3-methyl-3-cephem-4-carboxylic acid Chemical Properties
- Melting point:
- 234°C (dec.)
- Boiling point:
- 517.6±50.0 °C(Predicted)
- Density
- 1.59±0.1 g/cm3(Predicted)
- vapor pressure
- 0Pa at 20℃
- refractive index
- 104 ° (C=1, 1mol/L HCl)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 3.04±0.50(Predicted)
- form
- powder
- color
- White to Orange to Green
- Water Solubility
- Soluble in water (partly), 1M ammonium hydroxide (50 mg/ml), and DMSO (Sparingly).
- BRN
- 5273616
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C8H10N2O3S/c1-3-2-14-7-4(9)6(11)10(7)5(3)8(12)13/h4,7H,2,9H2,1H3,(H,12,13)/t4-,7-/m1/s1
- InChIKey
- NVIAYEIXYQCDAN-CLZZGJSISA-N
- SMILES
- N12[C@@]([H])([C@H](N)C1=O)SCC(C)=C2C(O)=O
- LogP
- -3.8--2.8 at 20℃ and pH3.6-7
- CAS DataBase Reference
- 22252-43-3(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 42/43-36/37/38-20/21/22
- Safety Statements
- 36-26
- WGK Germany
- 3
- HS Code
- 2941901010
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7-Amino-3-methyl-3-cephem-4-carboxylic acid Usage And Synthesis
Chemical Properties
Off-White Powder
Uses
A metabolite of Cephalexin (C256800).
Uses
7-Aminodesacetoxycephalosporanic acid is the Cephalexin metabolite. It is a Potent inhibitor of bacterial cell-wall enzyme. It is used in the synthesis of cephalosporins and for bioconversion studies.
Definition
ChEBI: A cephem monocarboxylic acid derivative having a structure based on cephalosporanic acid, deacetoxylated and carrying a 7beta-amino group.
Biological Activity
7-ADCA is produced from penicillin G made by Penicillium chrysogenum involving several polluting chemical steps followed by enzymatic deacylation using penicillin acylase .
7-Amino-3-methyl-3-cephem-4-carboxylic acid Preparation Products And Raw materials
Preparation Products
7-Amino-3-methyl-3-cephem-4-carboxylic acidSupplier
Suizhou Jiake Biological Engineering Co., Ltd. Gold
- Tel
- 0722-3632989 18008664499
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Jinan Wanduoxin Chemical Co., Ltd. Gold
- Tel
- 0531-88770993 13905318421
- wonderfulchem@163.com
Wuhan Dingtong Pharmaceutical Co., Ltd Gold
- Tel
- 027-027-59207795 18327179646
- 18327179646@163.com
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006356688 18621169109
- market03@meryer.com
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7-Amino-3-methyl-3-cephem-4-carboxylic acid(22252-43-3)Related Product Information
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