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ChemicalBook >  Product Catalog >  Organic Chemistry >  Ketones >  (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one

(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one

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(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one Basic information

Product Name:
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
Synonyms:
  • (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
  • E-0671
  • 5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (E,E,E)-
  • (5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
  • (5E,9E,13E)-Geranylgeranylacetone
  • 5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (5E,9E,13E)-
  • 13E)-Geranylgeranylacetone
  • 13E)-Teprenone
CAS:
3796-63-2
MF:
C23H38O
MW:
330.55
Mol File:
3796-63-2.mol
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(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one Chemical Properties

Boiling point:
442.2±24.0 °C(Predicted)
Density 
0.872±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 5 mg/mL (15.13 mM)
form 
Liquid
color 
Colorless to light yellow
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(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one Usage And Synthesis

Uses

(5E,9E,13E)-Teprenone is an isomer of Teprenone (T103500), An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Reports indicate that Teprenone protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression.

Definition

ChEBI: Teprenone is a terpene ketone in which a (9E,13E)-geranylgernayl group is bonded to one of the alpha-methyls of acetone (it is a mixture of 5E- and 5Z-geoisomers in a 3:2 ratio). It has a role as an anti-ulcer drug, a cardioprotective agent, a hepatoprotective agent, a nephroprotective agent, a neuroprotective agent and a Hsp70 inducer. It is a methyl ketone and a terpene ketone. It contains a geranylgeranyl group.

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