2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester Chemical Properties

Melting point:

91-94 °C

Boiling point:

640.5±55.0 °C(Predicted)

Density 

1.497±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

form 

Amorphous.

pka

8.61±0.40(Predicted)

color 

White to off-white

Safety Information

HS Code 

29419000

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester Usage And Synthesis

Description

Butyrolactone II is a butenolide fungal metabolite that has been found in A. terreus. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS free radicals (EC₅₀s = 11.5 and 68.5 μM, respectively). It inhibits 5-lipoxygenase (5-LO; IC₅₀ = 21.43 μg/ml) and α-glucosidase (IC₅₀ = 0.126 mM).

Uses

Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity.

storage

+4°C

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester(87414-44-6)Related Product Information

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