Periglaucine B
Periglaucine B Basic information
- Product Name:
- Periglaucine B
- Synonyms:
-
- Periglaucine B
- (7beta,8beta,10beta)-8,10-Epoxy-7,8-dimethoxy-17-methyl-2,3-[methylenebis(oxy)]-hasubanan-6-one
- Hasubanan-6-one, 8,10-epoxy-7,8-dimethoxy-17-methyl-2,3-[methylenebis(oxy)]-, (7β,8β,10β)-
- CAS:
- 1025023-05-5
- MF:
- C20H23NO6
- MW:
- 373.39972
- Mol File:
- 1025023-05-5.mol
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Periglaucine B Chemical Properties
- Boiling point:
- 509.5±50.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- pka
- 6.65±0.60(Predicted)
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Periglaucine B Usage And Synthesis
Uses
Periglaucine B ((+)-Periglaucine B) is an alkaloid and an HBsAg inhibitor. Periglaucine B can be isolated from Pericampylus glaucus. Periglaucine B inhibits the secretion of hepatitis B virus (HBV) surface antigen (HBsAg) in Hep G2.2.15 cells with an IC50 of 0.47 mM[1].
Definition
ChEBI: Periglaucine B is an isoquinoline alkaloid. It has a role as a metabolite.
References
[1] Yan MH, et al. Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus. J Nat Prod. 2008 May;71(5):760-3. DOI:10.1021/np070479+
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