N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Chemical Properties

Boiling point:

515.5±50.0 °C(Predicted)

Density 

1.529±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

pka

5.07±0.70(Predicted)

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Usage And Synthesis

Uses

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine(179552-74-0)Related Product Information

• Afatinib iMpurity
• 4-Hydroxy 4-Dedimethylamino Afatinib
• Afatinib-d6
• Afatinib IMpurity H
• Afatinib Impurity 74
• Afatinib impurity 40
• Afatinib impurity 33
• TRANS-4-AMINOCROTONIC ACID
• Afatinib Impurity L (Afatinib N-Oxide)
• Afatinib Impurity 22
• Afatinib impurity 30
• 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
• Afatinib impurity 27
• Afatinib impurity 34
• Afatinib impurity 41
• Afatinib Impurity I
• Afatinib-d4
• Afatinib Impurity K