Basic information Safety Supplier Related

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine

Basic information Safety Supplier Related

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Basic information

Product Name:
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
Synonyms:
  • N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
  • N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine
  • (3-chloro-4-fluoro-phenyl)-(7-methoxy-6-nitro-quinazolin-4-yl)-amine
  • 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-
  • Afatinib Impurity 137
  • N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinam...
  • N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
  • N - (3-Chloro-4-fluorophenyl) -7-methoxy-6-nitroquinoline-4-amine
CAS:
179552-74-0
MF:
C15H10ClFN4O3
MW:
348.72
EINECS:
207-985-8
Mol File:
179552-74-0.mol
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N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Chemical Properties

Boiling point:
515.5±50.0 °C(Predicted)
Density 
1.529±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
5.07±0.70(Predicted)
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N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Usage And Synthesis

Uses

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMineSupplier

Adamas Reagent, Ltd.
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400-6009262 16621234537
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
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BOC Sciences
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SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
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Shanghai Famo Bio-chemical Technology Company Ltd.
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021-36680027 15821745250
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fengqiang@famobiotech.com