3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Chemical Properties

Melting point:

233-237 °C

Boiling point:

403.7±45.0 °C(Predicted)

Density 

1.282±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

9.60±0.20(Predicted)

color 

Pale Yellow

InChIKey

LKLSFDWYIBUGNT-UHFFFAOYSA-N

CAS DataBase Reference

22246-18-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-43

Safety Statements 

36/37

WGK Germany 

3

HS Code 

29334900

MSDS

• Language:English Provider:SigmaAldrich

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Usage And Synthesis

Description

3,4-Dihydro-7-hydroxy-2 (1H)-quinolinone is a useful organic and pharmaceutical intermediate. It can be used as the precursor of aripiprazole1, which is an antipsychotic medication. It is also an antitumor agent and hydroxyindole analog inhibitor tyrosinase melanoma.

Chemical Properties

Pale Yellow Powder

Uses

3,4-Dihydro-7-hydroxyquinoline-2(1H)-one (Aripiprazole EP Impurity A) is an antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma. This compound is also used in the preparation of aripiprazole (A771000).

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone(22246-18-0)Related Product Information

• 4'-Hydroxyacetophenone
• CHLOROPHOSPHONAZO III
• Quinhydrone
• 2'-Hydroxyacetophenone
• 2-Quinolinol
• Tetrahydro-4H-pyran-4-one
• Neosperidin dihydrochalcone
• 1-Tetralone
• 8-Hydroxyquinoline
• Dehydroepiandrosterone
• 7-Hydroxyquinolinone
• 7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE
• Brexpiprazole Impurity 20
• Brexpiprazole Impurity 5 HCl
• 7-(4-chlorobutoxy)-1-{4-[(2-oxo-1,2-dihydroquinolin-7-yl)oxy]butyl}-1,2-dihydroquinolin-2-one
• (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE
• 5-HYDROXY-2(1H)-QUINOLINONE
• 7,7'-(butane-1,4-diylbis(oxy))bis(quinolin-2(1H)-one)