ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > Aprepitant Impurity 9
Aprepitant Impurity 9
Aprepitant Impurity 9 Basic information
- Product Name:
- Aprepitant Impurity 9
- Synonyms:
-
- Aprepitant Impurity 9
- Aprepitant Open-Ring Methyl Ester Impurity
- 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester
- Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity
- Aprepitant Impurity 47
- Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate
- Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
- methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
- CAS:
- 219821-37-1
- MF:
- C24H25F7N4O4
- MW:
- 566.47
- Mol File:
- 219821-37-1.mol
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Aprepitant Impurity 9 Chemical Properties
- Density
- 1.43±0.1 g/cm3(Predicted)
- solubility
- soluble in Chloroform, Dichloromethane, Methanol
- form
- Solid
- pka
- 7.86±0.43(Predicted)
- color
- Pale-Yellow
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Aprepitant Impurity 9 Usage And Synthesis
Uses
N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.
Aprepitant Impurity 9Supplier
ChemStrong Scientific Co.,Ltd
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Aprepitant Impurity 9(219821-37-1)Related Product Information
- Aprepitant-M3 Metabolite
- 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE
- Aprepitant
- Aprepitant Impurity 6
- Fosaprepitant Impurity 6
- 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one
- Aprepitant
- (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
- Aprepitant Impurity 17
- (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
- Fosaprepitant Benzyl Ester
- [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
- (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine
- Defluoro Aprepitant
- Aprepitant Impurity A Enantiomer
- 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
- Aprepitant Impurity 11 HCl
- Aprepitant Impurity 2