4-(7-methoxyquinolin-4-yl)-2-methylphenol Chemical Properties

Boiling point:

429.7±45.0 °C(Predicted)

Density 

1.201±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

solubility 

DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml

form 

A crystalline solid

pka

8.47±0.20(Predicted)

4-(7-methoxyquinolin-4-yl)-2-methylphenol Usage And Synthesis

Uses

CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.

storage

Store at -20°C

4-(7-methoxyquinolin-4-yl)-2-methylphenol(2165340-32-7)Related Product Information

• Tilorone dihydrochloride
• CU-CPT17e
• CU-CPT-8m
• CU-CPT-9a