Basic information Safety Supplier Related

Melengestrol acetate

Basic information Safety Supplier Related

Melengestrol acetate Basic information

Product Name:
Melengestrol acetate
Synonyms:
  • 20-dione,17-(acetyloxy)-6-methyl-16-methylene-pregna-6-diene-3
  • 6-dehydro-16-methylene-6-methyl-17-acetoxyprogesterone
  • 6-diene-3,20-dione,17-hydroxy-6-methyl-16-methylene-pregna-acetate
  • 5373
  • NSC-70968
  • 17-(Acetyloxy)-6-methyl-16-methylenepregna-4,6-diene-3,20-dione
  • 17-Hydroxy-6-methyl-16-methylenepregna-4,6-diene-3, 20-dione acetate
  • 6-Methyl-16-methylene-3,20-dioxopregna-4,6-dien-17-yl acetate
CAS:
2919-66-6
MF:
C25H32O4
MW:
396.52
EINECS:
220-859-7
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Hormone
  • Steroids
  • Steroid and Hormone
Mol File:
2919-66-6.mol
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Melengestrol acetate Chemical Properties

Melting point:
202-204 °C(lit.)
alpha 
D23 -127° (c = 0.31 in chloroform)
Boiling point:
440.2°C (rough estimate)
Density 
1.0911 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
0-6°C
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Beige
BRN 
2066919
InChIKey
UDKABVSQKJNZBH-DWNQPYOZSA-N
SMILES
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(C)=O)(C(=O)C)C(=C)C3)C=C2C
CAS DataBase Reference
2919-66-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
62
Safety Statements 
36
WGK Germany 
3
RTECS 
TU4141000
HS Code 
29372390
Toxicity
LD50 (mg/kg): >8000 orally in rats; >2500 i.p. in mice (Zimbelman)

MSDS

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Melengestrol acetate Usage And Synthesis

Chemical Properties

Light Tan Solid

Uses

antiarrhythmic, cardiotonic, hypertensive, Na/K ATPase inhibitor

Uses

Melengestrol Acetate is an orally active progestational steroid. Progestogen; growth promotant.

Definition

ChEBI: Melengestrol acetate is a corticosteroid hormone.

Safety Profile

An experimental teratogen. Experimental reproductive effects. When heated to decomposition it yields acrid smoke and irritating fumes.

Toxics Screening Level

The initial threshold screening level (ITSL) for melengesterol acetate is 2 μg/m3 based on an annual averaging time.

Melengestrol acetateSupplier

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