(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt
(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Basic information
- Product Name:
- (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt
- Synonyms:
-
- NEU5AC-A-4MU
- NEU5AC-ALPHA-4MU SODIUM SALT
- 2'-(4-METHYLUMBELLIFERYL)-A-D-N-ACETYLNEURAMINIC ACID, SODIUM SALT
- 2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT
- 4-MU-NANA NA
- 2-(4-methylumbelliferyl)-A-D-N-*acetylneuraminic
- Sodium 2-(4-methylumbelliferyl)-N-acetylneuraminate
- 4-methylumbelliferyl-N-acetyl-alpha-D-neuram.A.so-S.dihy.
- CAS:
- 76204-02-9
- MF:
- C21H26NNaO11
- MW:
- 491.42
- EINECS:
- 1533716-785-6
- Product Categories:
-
- substrate
- Carbohydrates & Derivatives
- Fluorescent Labels & Indicators
- Mol File:
- 76204-02-9.mol
(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Chemical Properties
- Melting point:
- 171°C dec.
- storage temp.
- −20°C
- solubility
- H2O: 50 mg/mL, clear, very slightly yellow
- form
- Solid
- color
- White to Off-White
(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Usage And Synthesis
Description
4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.
Chemical Properties
Off-White to Yellow Solid
Uses
Used as a substrate in a fluorometric assay of neuraminidase.
Uses
(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt has been used for fluorometric assay of neuraminidase as well as fluorescent staining of sialidases in PAGE.
Biochem/physiol Actions
Substrate for fluorometric assay of neuraminidase. Used for fluorescent staining of sialidases in PAGE.
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(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt(76204-02-9)Related Product Information
- SODIUM 4-HYDROXYBUTYRATE
- Sodium octanoate
- 4-AMINOBUTYRALDEHYDE DIMETHYL ACETAL
- ENANTHIC ACID SODIUM SALT
- [(2-OXO-2H-CHROMEN-7-YL)OXY]ACETIC ACID
- Sodium lactate
- (4-METHYLPHENOXY)ACETIC ACID
- (R)-(+)-2-PHENOXYPROPIONIC ACID
- 3-METHOXYPHENOXYACETIC ACID
- 4-ETHYLPHENOXYACETIC ACID
- ACETALDEHYDE, PARA-METHYL PHENOXY
- PELARGONIC ACID SODIUM SALT
- Phenoxyacetic acid sodium salt
- 2-Hydroxycaprylic acid
- N-Acetylneuraminic acid
- (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt
- DL-2-HYDROXYVALERIC ACID SODIUM SALT
- 2-(4-ETHYLPHENOXY)PROPANOIC ACID