ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Amide > N-Carbethoxyphthalimide
N-Carbethoxyphthalimide
N-Carbethoxyphthalimide Basic information
- Product Name:
- N-Carbethoxyphthalimide
- Synonyms:
-
- 1,3-dihydro-1,3-dioxo-2h-isoindole-2-carboxylicaciethylester
- 1,3-dioxo-2-isoindolinecarboxylicaciethylester
- N-(Carboethoxy)phthalimide~Nefkens
- Ethyl phthalimidocarboxylate
- N-Ethoxycarbonylphthalimide [for Peptide synthesis]
- N-Carbethoxyphthalimide, 98+%
- N-Carbethoxyphthalimide, 99+%
- 2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester
- CAS:
- 22509-74-6
- MF:
- C11H9NO4
- MW:
- 219.19
- EINECS:
- 245-048-5
- Product Categories:
-
- Biochemistry
- N-Substituted Maleimides, Succinimides & Phthalimides
- N-Substituted Phthalimides
- Peptide Synthesis
- Protection & Derivatization Reagents (for Synthesis)
- Protective Reagents (Peptide Synthesis)
- Synthetic Organic Chemistry
- Mol File:
- 22509-74-6.mol
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N-Carbethoxyphthalimide Chemical Properties
- Melting point:
- 90-92 °C(lit.)
- Boiling point:
- 360°C (rough estimate)
- Density
- 1.3219 (rough estimate)
- vapor pressure
- 0.003-0.006Pa at 20-25℃
- refractive index
- 1.4950 (estimate)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- -3.02±0.20(Predicted)
- color
- White
- Water Solubility
- insoluble
- BRN
- 196340
- InChIKey
- VRHAQNTWKSVEEC-UHFFFAOYSA-N
- LogP
- 1.1 at 20℃ and pH6.6-6.9
- CAS DataBase Reference
- 22509-74-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 2H-isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester(22509-74-6)
- EPA Substance Registry System
- 2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester (22509-74-6)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 22-24/25-36/37/39-26-36
- WGK Germany
- 3
- RTECS
- NR3459500
- F
- 10
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 29251995
MSDS
- Language:English Provider:Ethyl phthalimidocarboxylate
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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N-Carbethoxyphthalimide Usage And Synthesis
Chemical Properties
White crystalline powder
Uses
N-Carbethoxyphthalimide is used in the synthetic preparation of a novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Purification Methods
Crystallise the imide from toluene/pet ether (or *benzene/pet ether). It is partly soluble in Et2O, *benzene and CHCl3. [Heller & Jacobsohn Chem Ber 54 1112 1921, Beilstein 21/10 V 428.]
N-Carbethoxyphthalimide Preparation Products And Raw materials
Preparation Products
N-CarbethoxyphthalimideSupplier
Suzhou Highfine Biotech Co., Ltd Gold
- Tel
- 0512-68417696 13962195629
- qirl@highfine.com
Beijing Taiya Jie Technology Development Co., Ltd. Gold
- Tel
- 021-33690831-8001 13552411790
- postmaster@tyjchem.cn
Creasyn Finechem(Tianjin) Co., Ltd.
- Tel
- 022-022-83946278 13820372920
- sales@creasyn.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com