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3-(Trifluoromethyl)pyridine-2-carboxylic acid

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3-(Trifluoromethyl)pyridine-2-carboxylic acid Basic information

Product Name:
3-(Trifluoromethyl)pyridine-2-carboxylic acid
Synonyms:
  • 3-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID
  • 3-(TRIFLUOROMETHYL)PICOLINIC ACID
  • 3-(TRIFLUOROMETHYL)-2-PICOLINIC ACID
  • 3-(trifluoromethyl)-2-pyridinecarboxylic acid
  • 3-(Trifluoromethy)pyridine-2-carboxylic acid
  • 3-(Trifluoromethyl)-2-pyridinecarboxylicacid(en)
  • 3-(Trifluoromethyl)picolinic acid, 2-Carboxy-3-(trifluoromethyl)pyridine
  • 2-Pyridinecarboxylic acid, 3-(trifluoromethyl)-
CAS:
87407-12-3
MF:
C7H4F3NO2
MW:
191.11
Product Categories:
  • Carboxylic Acids
  • Pyridines
  • Acids and Derivatives
  • Heterocycles
  • Carboxylic Acids
  • Fluorine series
  • Aromatics
  • Intermediates
Mol File:
87407-12-3.mol
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3-(Trifluoromethyl)pyridine-2-carboxylic acid Chemical Properties

Melting point:
125-130°C
Boiling point:
274.4±40.0 °C(Predicted)
Density 
1.484±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
2.67±0.36(Predicted)
color 
Off-White
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Safety Information

Hazard Codes 
Xi,T
Risk Statements 
25-36/37/38
Safety Statements 
26-45
RIDADR 
2811
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
HS Code 
2933399990
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3-(Trifluoromethyl)pyridine-2-carboxylic acid Usage And Synthesis

Uses

Picolinic acid (P437220) derivative used in the synthesis of oxazine derivatives that act as BACE inhibitors for treatment of diabetes and neurological disorders.

Uses

As Picolinic acid (P437220) derivative, 3-(Trifluoromethyl)pyridine-2-carboxylic acid can be used in the synthesis of oxazine derivatives that act as BACE inhibitors for treatment of diabetes and neurological disorders.

Synthesis Reference(s)

Tetrahedron, 50, p. 12259, 1994 DOI: 10.1016/S0040-4020(01)89575-2

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