Thiazole-5-carboxaldehyde Chemical Properties

Melting point:

229 °C (decomp)

Boiling point:

92-94 °C/16 mmHg

Density 

1.304 g/mL at 25 °C

refractive index 

1.5874

Flash point:

98 °C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to lump to clear liquid

pka

0.94±0.10(Predicted)

color 

White or Colorless to Yellow

InChIKey

ZXRLWHGLEJGMNO-UHFFFAOYSA-N

CAS DataBase Reference

1003-32-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-43-36-22

Safety Statements 

26-36/37/39-36/37

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29341000

Thiazole-5-carboxaldehyde Usage And Synthesis

Chemical Properties

White to brown liquid or solid

Uses

Thiazole-5-carboxaldehyde is used in the synthesis of imidazoles with cardiomyocyte proliferation activity for heart disease treatments.

Synthesis Reference(s)

Synthetic Communications, 25, p. 4081, 1995 DOI: 10.1080/00397919508011485
Synthesis, p. 998, 1987 DOI: 10.1055/s-1987-28146

Purification Methods

Dry the aldehyde over Na2SO4 and fractionate it in a vacuum. The 2,4-dinitrophenylhydrazone forms red crystals from MeOH with m 238-240o, and the semicarbazone has m 210-212o (from MeOH). [Erne et al. Helv Chim Acta 34 148 1951, Beilstein 27 III/IV 2615.]

Thiazole-5-carboxaldehyde(1003-32-3)Related Product Information

• 2-Mercaptobenzothiazole
• Thiazole
• Formaldehyde
• Fosthiazate
• Benzothiazole
• Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)
• 2-(2-Aminothiazol-4-yl)glyoxylic acid
• Thiazole-4-carboxaldehyde
• Thiazole-5-carboxylic acid
• THIAZOLE-2-CARBOXYLIC ACID
• THIAZOLE-4-CARBOXAMIDE
• THIAZOLE-4-CARBOXYLIC ACID HYDRAZIDE
• 4-Thiazolecarboxylic acid
• THIAZOLE-5-CARBOXYLIC ACID HYDRAZIDE
• THIAZOLE ORANGE
• 1,3-Thiazole-2-carbaldehyde
• Ethyl 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylate
• Bleomycin