Isoviolanthin
Isoviolanthin Basic information
- Product Name:
- Isoviolanthin
- Synonyms:
-
- Isoviolanthin
- 4H-1-Benzopyran-4-one, 6-(6-deoxy-α-L-mannopyranosyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-
- TGF-beta/Smad,Transforming growth factor beta,normal liver LO2 cells,TGF-β1 EMT,Isoviolanthin,hepatocellular carcinoma cells cytotoxic effects,Inhibitor,inhibit
- 5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-6-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)-4H-chromen-4-one
- Isoviolanthin, 10 mM in DMSO
- CAS:
- 40788-84-9
- MF:
- C27H30O14
- MW:
- 578.52
- Mol File:
- 40788-84-9.mol
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Isoviolanthin Chemical Properties
- Boiling point:
- 925.3±65.0 °C(Predicted)
- Density
- 1.703±0.06 g/cm3(Predicted)
- pka
- 5.70±0.40(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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Isoviolanthin Usage And Synthesis
Uses
Isoviolanthin, a flavonoid glycoside, could markedly inhibit TGF-β1-mediated migration and invasion by deactivating epithelial-mesenchymal transition (EMT) via the TGF-β/Smad and PI3K/Akt/mTOR pathways in HCC cells. Isoviolanthin exhibits no cytotoxic effects on normal liver LO2 cells[1].
References
[1] Xing S, et al. Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial?Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways. Int J Mol Sci. 2018 May 23;19(6). DOI:10.3390/ijms19061556
IsoviolanthinSupplier
ShangHai YuanYe Biotechnology Co., Ltd.
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- 021-61312847 13636370518
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Chengdu Biopurify Phytochemicals Ltd.
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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Shandong Xiya Chemical Co., Ltd.
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- 4009903999 13395398332
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Chengdu Push Bio-Technology Co., Ltd.
- Tel
- 028-028-85370565-229-229 18080489829
- 18080489829@163.com
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