4-BROMO-1-BUTYNE Chemical Properties

Boiling point:

110 °C

Density 

1.417 g/mL at 25 °C

refractive index 

1.481

Flash point:

24 °C

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

clear liquid

color 

Colorless to Light yellow to Light orange

Water Solubility 

Immiscible with water.

InChIKey

XLYOGWXIKVUXCL-UHFFFAOYSA-N

Safety Information

Hazard Codes 

T

Risk Statements 

10-25-43

Safety Statements 

36/37-45

RIDADR 

UN 1992 6.1(3) / PGIII

WGK Germany 

3

HazardClass 

3

PackingGroup 

III

HS Code 

29039990

4-BROMO-1-BUTYNE Usage And Synthesis

Chemical Properties

Yellow liquid

Uses

4-Bromo-1-butyne is used for pharmaceutical intermediates.

Uses

4-Bromo-1-butyne is used as a reactant in the synthesis of:

• Macrocycles by cobalt-mediated [2+2+2] co-cyclotrimerization.
• 2,4,5-trisubstituted oxazoles by a gold-catalyzed formal [3+2] cycloaddition.
• Intramolecular 1,3-dipolar cycloaddition to synthesize 1,3,4-oxadiazoles.
• Lactones bearing alkynes for reductive cyclization in the preparation of azulene derivatives.
• Substituted α-pyrones by gold-catalyzed coupling reactions.

4-BROMO-1-BUTYNE(38771-21-0)Related Product Information

• Bromisoval
• 2-Butynoic acid
• 1-BUTYNE
• 2-Methyl-4-bromo-3-butyne-2-ol
• 1-Bromo-1-butyne
• 2-Bromo-3-Butyne
• 3-Bromo-1-butyne
• 1-BROMO-2-BUTYNE,1-BROMO-2-BUTYNE 98%
• 4-BROMO-1-BUTYNE
• 1,1,1-TRIBROMO-4-PHENYL-BUT-3-YN-2-OL
• 1-BROMO-3-HEXYNE
• 1-BROMO-1-PHENYL-4-TRIMETHYLSILANYL-BUT-3-YN-2-ONE