5-Methyltetrahydrofolic acid Chemical Properties

Melting point:

>300°C (dec.)

Density 

1.62±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Aqueous Base (Slightly, Sonicated)

form 

Solid

pka

3.51±0.10(Predicted)

color 

Pale Beige

Stability:

Hygroscopic

5-Methyltetrahydrofolic acid Usage And Synthesis

Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

Supplements

5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

Mechanism of Action

Prefolic A, also known as 5-Methyltetrahydrofolate, is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine. Methyl folate is an active metabolite of folic acid. Vitamin supplement in health care products.

Shipping & Storage Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Stored in dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Shelf Life can be more than 2 years if stored properly.

Chemical Properties

Off-White Solid

Uses

5-Methyltetrahydrofolic acid-(glutamic acid-¹³C₅) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

Uses

5-Methyltetrahydrofolic acid is a metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

General Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group.
5-Methyltetrahydrofolic acid-(glutamic acid-¹³C₅) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by ¹³C₆ carbon.

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