2-Amino-4-hydroxy-1H-pteridine Chemical Properties

Melting point:

300 °C

Boiling point:

290.2°C (rough estimate)

Density 

1.4240 (rough estimate)

refractive index 

1.9000 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

pka

2.27(at 20℃)

form 

powder

biological source

synthetic

Water Solubility 

17.54mg/L(22.5 ºC)

BRN 

150294

InChIKey

HNXQXTQTPAJEJL-UHFFFAOYSA-N

CAS DataBase Reference

2236-60-4(CAS DataBase Reference)

NIST Chemistry Reference

4(1H)-pteridinone, 2-amino-(2236-60-4)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

RTECS 

UO3505000

F 

10-23

HS Code 

29335990

MSDS

• Language:English Provider:2-Amino-4-hydroxy-1H-pteridine
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2-Amino-4-hydroxy-1H-pteridine Usage And Synthesis

Chemical Properties

YELLOW-BEIGE CRYSTALLINE POWDER

Uses

Pterin is used in the biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.

Definition

ChEBI: 2-aminopteridin-4-ol is a 2-amino-4-hydroxypteridine. It is a tautomer of a 2-aminopteridin-4(3H)-one and a 2-aminopteridin-4(1H)-one.

Biological Activity

Pterine consists of pyrazine and pyrimidine with substitutions in keto and amino group. Pterine is present in all organisms including cyanobacteria. It acts as a cofactor for redox enzymes and serves as a precursor for folic acid synthesis. Pterine from the butterfly wings absorb light and elicit incoherent scattering. Pterine induces alterations in DNA by hydroxylation of deoxyguanosine.

Purification Methods

It is dissolved in hot 1% aqueous ammonia, filtered, and an equal volume of hot 1M aqueous formic acid is added. The solution is allowed to cool at 0-2o overnight. The solid is collected and washed with distilled water several times by centrifugation and dried in vacuo over P2O5 overnight, and then at 100o overnight (any ammonium formate in the sample evaporates off). [Beilstein 26 III/IV 3936.]

2-Amino-4-hydroxy-1H-pteridine(2236-60-4)Related Product Information

• Acetaminophen
• CHLOROPHOSPHONAZO III
• Protocatechuic acid
• EC 2.6.1.2
• 2-Chloro-3-hydroxypyridine
• 3-Aminophenol
• ALTRENOGEST
• Glycine
• Triamterene
• 6-Aminocaproic acid
• Tris(hydroxymethyl)aminomethane
• 10-Formylfolic Acid
• 2-Amino-4-hydroxypteridine-6-methanol
• 2-Amino-7-(chloromethyl)pteridin-4(1H)-one
• Levomefolate calcium
• N-(p-Aminobenzoyl)glutamic acid
• Folic Acid Impurity C
• (2S)-2-[[4-[Bis[(2-aMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoyl]aMino]pentanedioic Acid