Basic information Safety Supplier Related

N-(4-aminobenzoyl)- D-Glutamic acid

Basic information Safety Supplier Related

N-(4-aminobenzoyl)- D-Glutamic acid Basic information

Product Name:
N-(4-aminobenzoyl)- D-Glutamic acid
Synonyms:
  • N-(4-aminobenzoyl)- D-Glutamic acid
  • 4-Aminobenzoyl D-Glutamic Acid
  • Methotrexate EP Impurity K(Amethopterin EP Impurity K)
  • Folinic Acid Impurity 5
  • Folic Acid Impurity 16
  • Folinic Acid Impurity 5 (4-Aminobenzoyl D-Glutamic Acid)
  • D-Glutamic acid, N-(4-aminobenzoyl)-
CAS:
5959-18-2
MF:
C12H14N2O5
MW:
266.25
Mol File:
5959-18-2.mol
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N-(4-aminobenzoyl)- D-Glutamic acid Chemical Properties

Boiling point:
607.1±55.0 °C(Predicted)
Density 
1.418±0.06 g/cm3(Predicted)
solubility 
Dichloromethane, Ethyl Acetate, Methanol, Water
form 
Solid
pka
3.50±0.10(Predicted)
color 
Pale Yellow
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N-(4-aminobenzoyl)- D-Glutamic acid Usage And Synthesis

Uses

N-(4-Aminobenzoyl)-D-glutamic acid is an intermediate in the synthesis of R-Methotrexate which is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

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