2-HYDROXYCYCLOHEXANONE DIMER Chemical Properties

Melting point:

100-107 °C(lit.)

Boiling point:

83-86 °C13 mm Hg(lit.)

Flash point:

175 °F

storage temp. 

2-8°C

form 

Powder

color 

Off-white

Water Solubility 

Partly miscible in water.

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

11-36/37/38

Safety Statements 

16-26-36

RIDADR 

UN 1325 4.1/PG 3

WGK Germany 

3

F 

9-21

HazardClass 

4.1

PackingGroup 

III

HS Code 

29144090

2-HYDROXYCYCLOHEXANONE DIMER Usage And Synthesis

Chemical Properties

Off-white powder

Uses

Reactant involved in:• ;Synthesis of substrated for tin tetrachloride mediated fragmentation to produce ynones and ynoates1• ;Tandem oxidation coupling reactions with diamines2• ;Asymmetric allylic alkylation of enolates3• ;Formate reduction of allylic carbonates for polypropionate systems4

Uses

It is a reactant involved in the synthesis of substrates for tin tetrachloride mediated fragmentation to produce ynones and ynoates, tandem oxidation coupling reactions with diamines, asymmetric allylic alkylation of enolates and formate reduction of allylic carbonates for polypropionate systems.

Uses

Reactant involved in:

• Synthesis of substrated for tin tetrachloride mediated fragmentation to produce ynones and ynoates
• Tandem oxidation coupling reactions with diamines
• Asymmetric allylic alkylation of enolates
• Formate reduction of allylic carbonates for polypropionate systems

Definition

ChEBI: 2-hydroxycyclohexan-1-one is a secondary alpha-hydroxy ketone and a hydroxycyclohexanone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 130, 1986 DOI: 10.1021/jo00352a002
Synthetic Communications, 25, p. 3141, 1995 DOI: 10.1080/00397919508015463
Tetrahedron Letters, 36, p. 3031, 1995 DOI: 10.1016/0040-4039(95)00419-D

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