Hydroxy O-Desmethyl Apixaban Chemical Properties

Boiling point:

844.9±65.0 °C(Predicted)

Density 

1.55±0.1 g/cm3(Predicted)

pka

8.56±0.15(Predicted)

Hydroxy O-Desmethyl Apixaban Usage And Synthesis

Uses

Hydroxy O-Demethyl Apixaban, is an impurity of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.

Hydroxy O-Desmethyl Apixaban(2204368-56-7)Related Product Information

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• Apixaban Impurity 7
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• Apixaban-13C-D3
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• Apixaban-d3
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• ethyl (E)-2-(2-(4-methoxyphenyl)hydrazono)propanoate
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• 2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-
• 4-Pyridineacetic acid, 1,2,5,6-tetrahydro-3-hydroxy-α,2-dioxo-1-[4-(2-oxo-1-piperidinyl)phenyl]-
• 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, 2-hydroxy-1-methylethyl ester
• 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, 2-hydroxypropyl ester