Apixaban Impurity 52 Chemical Properties

Boiling point:

830.7±65.0 °C(Predicted)

Density 

1.36±0.1 g/cm3(Predicted)

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

14.99±0.20(Predicted)

form 

Solid

color 

Pale Beige to Light Brown

Apixaban Impurity 52 Usage And Synthesis

Uses

Desmethyl-O-Benzyl Apixaban is a useful intermediate in the preparation of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. Apixaban Impurity.

Apixaban Impurity 52(1620494-31-6)Related Product Information

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• ethyl (E)-2-(2-(4-methoxyphenyl)hydrazono)propanoate
• 2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-
• 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, 2-hydroxypropyl ester
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• Hydroxy O-Desmethyl Apixaban
• 4-Pyridineacetic acid, 1,2,5,6-tetrahydro-3-hydroxy-α,2-dioxo-1-[4-(2-oxo-1-piperidinyl)phenyl]-