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O-DesmethylApixabanSulphateNa

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O-DesmethylApixabanSulphateNa Basic information

Product Name:
O-DesmethylApixabanSulphateNa
Synonyms:
  • O-DesmethylApixabanSulphateNa
  • Apixaban Impurity 105
  • 4,5,6,7-Tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1-[4-(sulfooxy)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
  • 1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 4,5,6,7-tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1-[4-(sulfooxy)phenyl]-
  • O-Demethyl apixaban sulfate
  • Apixaban Impurity 242
CAS:
1118765-14-2
MF:
C24H23N5O7S
MW:
525.53
Mol File:
1118765-14-2.mol
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O-DesmethylApixabanSulphateNa Chemical Properties

Density 
1.61±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
-4.98±0.18(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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O-DesmethylApixabanSulphateNa Usage And Synthesis

Uses

O-Desmethyl Apixaban Sulfate is an impurity of Apixaban (A726700), is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.

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