2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- Chemical Properties

Boiling point:

394.8±42.0 °C(Predicted)

Density 

1.34±0.1 g/cm3(Predicted)

pka

4.96±0.10(Predicted)

2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- Usage And Synthesis

Uses

1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.

2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-(1801881-15-1)Related Product Information

• 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
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• Hydroxy O-Desmethyl Apixaban Sulfate
• O-DesmethylApixabanSulphateNa
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• Apixaban-d3
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• ethyl (E)-2-(2-(4-methoxyphenyl)hydrazono)propanoate
• Hydroxy O-Desmethyl Apixaban
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• 4-Pyridineacetic acid, 1,2,5,6-tetrahydro-3-hydroxy-α,2-dioxo-1-[4-(2-oxo-1-piperidinyl)phenyl]-
• 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, 2-hydroxy-1-methylethyl ester
• 1-(4-Methoxyphenyl)-6-(4-iodophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
• Apixaban Impurity 51
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• 2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
• Apixaban Impurity 22