Boc-6-AMinocaproic acid Chemical Properties

Melting point:

35-40 °C

Boiling point:

166°C/0.3mmHg(lit.)

Density 

1.065±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform, Ethyl Acetate

pka

4.76±0.10(Predicted)

form 

Powder

color 

White

Water Solubility 

Soluble in chloroform and ethyl acetate. Slightly soluble in water.

BRN 

2049561

CAS DataBase Reference

6404-29-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-26

WGK Germany 

3

F 

21

HazardClass 

IRRITANT

HS Code 

29241990

MSDS

• Language:English Provider:SigmaAldrich

Boc-6-AMinocaproic acid Usage And Synthesis

Description

Boc-6-aminohexanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

Colorless crystal

Uses

6-(Boc-amino)hexanoic acid is used in the preparation of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carboxy peptidase, plasmin, and plasminogen activator.

Uses

Protected ε-Aminocaproic Acid (A603015), Boc-6-AMinocaproic acid can be used in the preparatiom of esters of 6-aminohexanoic acid.

Boc-6-AMinocaproic acid(6404-29-1)Related Product Information

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