2-METHYL-6-NITROBENZOIC ANHYDRIDE Chemical Properties

Melting point:

173-177 °C

Boiling point:

559.4±50.0 °C(Predicted)

Density 

1.416±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

very faint turbidity in hot Toluene

form 

powder to crystal

color 

White to Yellow to Orange

InChIKey

YEKPNMQQSPHKBP-UHFFFAOYSA-N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29163990

2-METHYL-6-NITROBENZOIC ANHYDRIDE Usage And Synthesis

Uses

2-Methyl-6-nitrobenzoic anhydride can be used:

• As a versatile lactonization reagent applicable in the preparation of varieties of macrolide natural products and lactones.
• As a reaction promoter in the synthesis of carboxamide derivatives by using corresponding amines and carboxylic acids.
• In the total synthesis of GRP78 inhibitor prunustatin A, antifungal compound (3R,16E,20E,23R)-(?)-eushearilide and an antiobestic drug tetrahydrolipstatin.

General Description

2-Methyl-6-nitrobenzoic anhydride is a reagent employed as a coupling promoter in the synthesis of amides, lactones, esters, and peptides.

2-METHYL-6-NITROBENZOIC ANHYDRIDE(434935-69-0)Related Product Information

• 2-METHYL-6-NITROBENZOIC ACID
• Benzoic anhydride
• METHYL-2METHYL-6-NITRO-BENZOATE
• 2-METHYL-6-NITROBENZOIC ANHYDRIDE