FAMPHUR Chemical Properties

Melting point:

53℃

Boiling point:

394.2±52.0 °C(Predicted)

Density 

1.354±0.06 g/cm3(Predicted)

vapor pressure 

3 x 10^-5 Pa (est. 20 °C)

Flash point:

>100 °C

storage temp. 

APPROX 4°C

form 

Liquid

Water Solubility 

5000 (est. 20 °C)

pka

-5.18±0.70(Predicted)

Merck 

13,3963

BRN 

2224254

EPA Substance Registry System

Famphur (52-85-7)

Safety Information

Hazard Codes 

T,Xn,F

Risk Statements 

24/25-36/38-63-43-36/37/38-23/24/25-45-67-40-39/23/24/25-11

Safety Statements 

22-24/25-45-36/37-23-53-16-7

RIDADR 

2783

WGK Germany 

3

RTECS 

TF7650000

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29350090

Hazardous Substances Data

52-85-7(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 35 mg/kg (Schafer)

FAMPHUR Usage And Synthesis

Chemical Properties

Crystalline powder. Very soluble in chloroform and carbon tetrachloride; slightly soluble in water.

Uses

Insecticide.

Definition

ChEBI: Famphur is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical and an anthelminthic drug. It is functionally related to a 4-hydroxy-N,N-dimethylbenzenesulfonamide.

General Description

Crystalline powder. Very toxic. Cholinesterase inhibitor. Restricted use as insecticide.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Organothiophosphates, such as FAMPHUR, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Hazard

Cholinesterase inhibitor, use may be restricted.

Metabolism

The principal degradation routes in mammals are P?Ophenyl bond cleavage and O-demethylation. Oxidative desulfuration and N-demethylation also take place to form toxic metabolites.

Toxicity evaluation

The acute oral LD₅₀ for rats is 35–62 mg/kg.

FAMPHUR(52-85-7)Related Product Information

• ATRAZINE-DESETHYL
• Trichlorfon
• ATRAZINE SOLUTION 100UG/ML IN T-BUTYLMETHYL ETHER 1ML
• Prometryn
• ETOXAZOLE
• CYFLUFENAMID
• FAMPHUR
• 4-Hydroxybenzenesulfonamide
• Cythioate
• TRIMETHYL THIOPHOSPHATE
• FAMPHUR-O-ANALOG,FAMPHUR-O-ANALOGUE,FAMPHUR-OXON
• P-HYDROXY-N,N-DIMETHYLBENZENE SULFONAMIDE
• N,N-Dipentyl-p-hydroxybenzenesulfonamide O,O-dimethyl phosphorothioate
• FAMPHUR SOLUTION 5X1ML
• FAMPHUR SOLUTION 100UG/ML IN ISOOCTANE 5X1ML
• FAMPHUR MIX 5X1ML MEOH 100UG/ML
• FAMPHUR SOLUTION 100UG/ML IN ISOOCTANE 5ML
• FAMPHUR SOLUTION 100UG/ML IN ISOOCTANE 1ML