Basic information Safety Supplier Related

ANGIOTENSIN I, HUMAN

Basic information Safety Supplier Related

ANGIOTENSIN I, HUMAN Basic information

Product Name:
ANGIOTENSIN I, HUMAN
Synonyms:
  • angiotensin I, Ile(5)-
  • Angiotensin I (human, rat, mouse)
  • human,mouse,rat
  • DRVYIHPFHL
  • HYPERTENSIN I HUMAN
  • H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-OH
  • H2N-DRVYIHPFHL-OH
  • ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-OH 2CH3COOH 6H2O
CAS:
484-42-4
MF:
C62H89N17O14
MW:
1296.48
Product Categories:
  • Angiotensin
  • SignalTransduction
Mol File:
484-42-4.mol
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ANGIOTENSIN I, HUMAN Chemical Properties

Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
≥129.6 mg/mL in DMSO; ≥124.2 mg/mL in H2O; ≥9.16 mg/mL in EtOH
form 
Powder
pka
3.27±0.10(Predicted)
color 
White
Water Solubility 
Soluble to 1 mg/ml in water.
Sequence
H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH
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ANGIOTENSIN I, HUMAN Usage And Synthesis

Uses

Angiotensin I (human) stimulates the release of aldosterone, another hormone, from the adrenal cortex. It acts as a precursor to angiotensin II. It acts as endogenous peptide substrate for angiotensin converting enzyme (ACE), precursor to the vasoconstrictor peptide angiotensin II

Definition

ChEBI: Angiotensin I is a ten amino acid peptide formed by renin cleavage of angiotensinogen. Angiotensin I has no direct biological function except that high levels can stimulate catecholamine production. It is metabolized to its biologically active byproduct angiotensin II, a potent vasoconstrictor, by angiotensin converting enzyme (ACE) through cleavage of the two terminal amino acids. It has a role as a neurotransmitter agent and a human metabolite. It is a tautomer of an angiotensin I dizwitterion.

storage

Store at -20°C

ANGIOTENSIN I, HUMANSupplier

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