Basic information Safety Supplier Related

Mal-amido-PEG8-val-gly-PAB-OH

Basic information Safety Supplier Related

Mal-amido-PEG8-val-gly-PAB-OH Basic information

Product Name:
Mal-amido-PEG8-val-gly-PAB-OH
Synonyms:
  • Mal-amido-PEG8-val-gly-PAB-OH
CAS:
2353409-52-4
MF:
C40H63N5O15
MW:
853.95
Product Categories:
  • ADC LINKER
Mol File:
2353409-52-4.mol
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Mal-amido-PEG8-val-gly-PAB-OH Chemical Properties

Boiling point:
1051.3±65.0 °C(Predicted)
Density 
1.231±0.06 g/cm3(Predicted)
pka
14.14±0.46(Predicted)
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Mal-amido-PEG8-val-gly-PAB-OH Usage And Synthesis

Uses

Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Mal-amido-PEG8-val-gly-PAB-OHSupplier

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