Basic information Safety Supplier Related

Mal-PEG1-Bromide

Basic information Safety Supplier Related

Mal-PEG1-Bromide Basic information

Product Name:
Mal-PEG1-Bromide
Synonyms:
  • Mal-PEG1-Bromide
  • 1H-Pyrrole-2,5-dione, 1-[2-(2-bromoethoxy)ethyl]-
  • 1-[2-(2-bromoethoxy)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione
  • 1-(2-(2-bromoethoxy)ethyl)-1H-pyrrole-2,5-dione
CAS:
1823885-81-9
MF:
C8H10BrNO3
MW:
248.07
Mol File:
1823885-81-9.mol
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Mal-PEG1-Bromide Chemical Properties

Boiling point:
358.1±22.0 °C(Predicted)
Density 
1.588±0.06 g/cm3(Predicted)
solubility 
Soluble in DMSO, DCM, DMF
pka
-2.35±0.20(Predicted)
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Mal-PEG1-Bromide Usage And Synthesis

Description

Mal-PEG1-Bromide contains a maleimide group and bromide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.

Uses

Mal-PEG1-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG1-BromideSupplier

Bide Pharmatech Ltd.
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400-164-7117 13681763483
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product02@bidepharm.com
Jinan elephant international trading co., LTD
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Email
13006575422@163.com
Alpha Biopharmaceuticals Co., Ltd
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0411-39042497
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sales@alphabiopharm.com
TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Nextpeptide Inc
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+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
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Mal-PEG1-Bromide(1823885-81-9)Related Product Information