Mal-amido-PEG7-acid CAS#: 2112731-42-5

Mal-amido-PEG7-acid Basic information

Product Name:

Mal-amido-PEG7-acid

Synonyms:

Mal-amido-PEG7-acid
Mal-NH-PEG7-acid
Mal-amido-PEG7-COOH
Mal-NH-PEG7-COOH
4,7,10,13,16,19,22-Heptaoxa-25-azaoctacosanoic acid, 28-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-26-oxo-
Mal-amido-PEG7-propionic acid
1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25-heptaoxa-4-azaoctacosan-28-oic acid
MalamidoPEG7acid,PROTAC Linkers,Mal amido PEG7 acid,inhibit,Inhibitor

CAS:

2112731-42-5

MF:

C24H40N2O12

MW:

548.58

Product Categories:

peg

Mol File:

2112731-42-5.mol

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Mal-amido-PEG7-acid Usage And Synthesis

Uses

Mal-amido-peg7-acid is a useful research chemical, a PEG linker and a PEG reagent.

Biological Activity

Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Mal-amido-PEG7-acidSupplier

Borenpharm Co., Ltd Gold

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Zhengzhou Acme Chemical Co., Ltd.

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Amatek Scientific Co. Ltd.

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