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colocynthin

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colocynthin Basic information

Product Name:
colocynthin
Synonyms:
  • colocynthin
  • Cocillana
  • (10α)-25-(Acetyloxy)-2-(β-D-glucopyranosyloxy)-16α,20-dihydroxy-9β-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione
  • 2-O-β-D-Glucopyranosylcucurbitacin E
  • Coloside A
  • α-Elaterin 2-D-glucopyranoside
  • Cucurbitacin E-2-O-Glucoside
  • alpha-Elaterin 2-D-glucopyranoside
CAS:
1398-78-3
MF:
C38H54O13
MW:
718.83
EINECS:
215-745-9
Product Categories:
  • Organics
Mol File:
1398-78-3.mol
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colocynthin Chemical Properties

Melting point:
158-160℃
alpha 
D +50° (c = 0.4 in ethanol)
Density 
1.35±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
-20°C
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Safety Information

RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
1
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colocynthin Usage And Synthesis

Uses

Cucurbitacin E 2-O-Glucoside is a metabolite of Cucurbitacin E (C838800), a highly oxidated steroid consisting of a tetracyclic triterpene. Cucurbitacin E is known to possess broad spectrum of potential anti-inflammatory, antitumor andantioxidant effects.

Definition

ChEBI: Cucurbitacin E 2-O-beta-D-glucopyranoside is a triterpenoid saponin that is cucurbitacin E attached to a beta-D-glucopyranosyl residue at position 2 via a glycosidic linkage. Isolated from Machilus yaoshansis it exhibits antineoplastic activity. It has a role as a plant metabolite and an antineoplastic agent. It is a cucurbitacin, a beta-D-glucoside, a monosaccharide derivative, a triterpenoid saponin, an acetate ester and a tertiary alpha-hydroxy ketone. It is functionally related to a cucurbitacin E.

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