4-Aminobenzonitrile Chemical Properties

Melting point:

83-85 °C(lit.)

Boiling point:

167 °C / 1mmHg

Density 

1.1151 (rough estimate)

vapor pressure 

0.002-0.005Pa at 20-25℃

refractive index 

1.5500 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Crystalline Powder Chunks

pka

1.74(at 25℃)

color 

Off-white or beige to orange-yellow

Water Solubility 

Soluble in ethyl acetate, dichloromethane and chloroform. Insoluble in water.

BRN 

774507

Stability:

Toxic

InChIKey

YBAZINRZQSAIAY-UHFFFAOYSA-N

LogP

1 at 20℃ and pH7

CAS DataBase Reference

873-74-5(CAS DataBase Reference)

NIST Chemistry Reference

Benzonitrile, 4-amino-(873-74-5)

EPA Substance Registry System

Benzonitrile, 4-amino- (873-74-5)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36-36/37/38-20/21/22

Safety Statements 

26-36

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

BX2320000

Hazard Note 

Harmful

TSCA 

T

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269095

MSDS

• Language:English Provider:p-Cyanoaniline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Aminobenzonitrile Usage And Synthesis

Chemical Properties

off-white or beige to orange-yellow crystalline

Uses

4-Aminobenzonitrile is an amino substituted benzonitrile with hypotensive activity. 4-Aminobenzonitrile is used as radioprotective agent

Uses

4-Aminobenzonitrile was used as derivatization reagent in capillary zone electrophoretic analysis of aldoses, ketoses and uronic acid. It was used in the synthesis of methacrylic monomers containing pendant azobenzene structures and polythiophenes containing an azobenzene moiety in the side-chain.

Uses

4-Aminobenzonitrile is used as an amino substituted benzonitrile with hypotensive activity and as a radioprotective agent. It is also used as a derivatization reagent in the capillary zone electrophoretic analysis of aldoses, ketoses and uronic acid. Further, it is used in the preparation of methacrylic monomers containing pendant azobenzene structures and polythiophenes containing an azobenzene moiety in the side-chain.

Purification Methods

It crystallises from water, 5% aqueous EtOH or EtOH and is dried over P2O5 or dried in vacuo for 6hours at 40o. [Moore et al. J Am Chem Soc 108 2257 1986, Edidin et al. J Am Chem Soc 109 3945 1987, Beilstein 14 IV 1158.]

4-Aminobenzonitrile(873-74-5)Related Product Information

• Sulfanilic acid
• METHYL 4-(4-AMINOPHENYL)BUTANOATE
• Sulfanilamide
• Phenetidine
• p-Anisidine
• 4-Aminobenzoic acid
• 4-Amino-benzenesulfonic acid monosodium salt
• 4-Aminobenzaldehyde
• 2-(4-Aminophenyl)ethanol
• 4-Iodoaniline
• p-Aminobenzamide
• 2-Aminobenzonitrile
• 3-Aminobenzonitrile;m-Cyanoaniline ,M-AMINOBENZONITRILE,3-AMINOBENZONITRILE
• 4-Nitrophthalonitrile
• 4-Amino-3,5-dichlorobenzonitrile
• 3,4-DINITROBENZONITRILE
• 4-[(4-METHOXYBENZYLIDENE)AMINO]BENZONITRILE
• 4-ACETAMIDOBENZONITRILE