Basic information Safety Supplier Related

4,4'-DIFLUOROBENZIL

Basic information Safety Supplier Related

4,4'-DIFLUOROBENZIL Basic information

Product Name:
4,4'-DIFLUOROBENZIL
Synonyms:
  • 1,2-Bis(4-fluorophenyl)-1,2-ethanedione
  • 4,4'-DIFLUOROBENZIL
  • 4,4'-DIFLUOROBIBENZOYL
  • 4,4'-DIFLUORODIBENZOYL
  • 4,4'-FLUOROBENZIL
  • BIS(P-FLUOROPHENYL)ETHANEDIONE
  • 4,4'-Difluorobenzil,99%
  • Ethanedione, bis(4-fluorophenyl)-
CAS:
579-39-5
MF:
C14H8F2O2
MW:
246.21
Product Categories:
  • Aryl Fluorinated Building Blocks
  • Bioactive Small Molecules
  • Building Blocks
  • C13 to C14
  • C13-C26
  • Carbonyl Compounds
  • C13 to C14
  • Cell Biology
  • Chemical Synthesis
  • D-DIF
  • Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • Aromatic Halides (substituted)
  • Carbonyl Compounds
  • Ketones
Mol File:
579-39-5.mol
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4,4'-DIFLUOROBENZIL Chemical Properties

Melting point:
120-122 °C (lit.)
Boiling point:
370.2±27.0 °C(Predicted)
Density 
1.3163 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
color 
Light orange to Yellow to Green
Water Solubility 
Soluble in water.
BRN 
1971736
CAS DataBase Reference
579-39-5(CAS DataBase Reference)
EPA Substance Registry System
Ethanedione, bis(4-fluorophenyl)- (579-39-5)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
T
HS Code 
29147000

MSDS

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4,4'-DIFLUOROBENZIL Usage And Synthesis

Chemical Properties

pale yellow powder

Uses

4,4′-Difluorobenzil is suitable for use in the preparation of 2,3-bis(4-fluorophenyl)thieno[3,4-b]pyrazine. It may be used in the synthesis of following:

  • poly(ether-α-diketone)s, via nucleophilic substitution reaction with bisphenol A
  • 4,4′-difluoro-2,3-diphenylpyrazine (DPPF) and 4,4′-difluoro-5-methyl 2,3-diphenylpyrazine (MDPPF), via direct condensation with ethylenediamine and 1,2-diaminopropane, respectively
  • 2,3-bis(4-fluorophenyl)quinoxaline, via direct condensation with 1,2-phenylenediamine

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 2959, 1994 DOI: 10.1016/S0040-4039(00)76671-8

General Description

4,4′-Difluorobenzil is a benzil derivative. Its reaction with benzylurea and phenethylurea has been investigated. It is reported to undergo condensation with Fe2(SH)2(CO)6 to afford the adduct Fe2[S2C2(OH)2(C6H4-4-F)2](CO)6.

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