Basic information Safety Supplier Related

4,4'-DIFLUOROBENZIL

Basic information Safety Supplier Related

4,4'-DIFLUOROBENZIL Basic information

Product Name:
4,4'-DIFLUOROBENZIL
Synonyms:
  • 1,2-Bis(4-fluorophenyl)-1,2-ethanedione
  • 4,4'-DIFLUOROBENZIL
  • 4,4'-DIFLUOROBIBENZOYL
  • 4,4'-FLUOROBENZIL
  • BIS(P-FLUOROPHENYL)ETHANEDIONE
  • 4,4'-Difluorobenzil,99%
  • Ethanedione, bis(4-fluorophenyl)-
  • 1-[anilino(oxo)methyl]-3-methyl-1,3-diphenylurea
CAS:
579-39-5
MF:
C14H8F2O2
MW:
246.21
Product Categories:
  • Aryl Fluorinated Building Blocks
  • Bioactive Small Molecules
  • Building Blocks
  • C13 to C14
  • C13-C26
  • Carbonyl Compounds
  • Cell Biology
  • Chemical Synthesis
  • D-DIF
  • Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • C13 to C14
  • Carbonyl Compounds
  • Ketones
  • Aromatic Halides (substituted)
Mol File:
579-39-5.mol
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4,4'-DIFLUOROBENZIL Chemical Properties

Melting point:
120-122 °C (lit.)
Boiling point:
370.2±27.0 °C(Predicted)
Density 
1.3163 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
color 
Light orange to Yellow to Green
Water Solubility 
Soluble in water.
BRN 
1971736
InChI
InChI=1S/C14H8F2O2/c15-11-5-1-9(2-6-11)13(17)14(18)10-3-7-12(16)8-4-10/h1-8H
InChIKey
BRKULQOUSCHDGS-UHFFFAOYSA-N
SMILES
C(C1=CC=C(F)C=C1)(=O)C(C1=CC=C(F)C=C1)=O
CAS DataBase Reference
579-39-5(CAS DataBase Reference)
EPA Substance Registry System
Ethanedione, bis(4-fluorophenyl)- (579-39-5)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
T
HS Code 
29147000

MSDS

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4,4'-DIFLUOROBENZIL Usage And Synthesis

Chemical Properties

pale yellow powder

Uses

4,4′-Difluorobenzil is suitable for use in the preparation of 2,3-bis(4-fluorophenyl)thieno[3,4-b]pyrazine. It may be used in the synthesis of following:

  • poly(ether-α-diketone)s, via nucleophilic substitution reaction with bisphenol A
  • 4,4′-difluoro-2,3-diphenylpyrazine (DPPF) and 4,4′-difluoro-5-methyl 2,3-diphenylpyrazine (MDPPF), via direct condensation with ethylenediamine and 1,2-diaminopropane, respectively
  • 2,3-bis(4-fluorophenyl)quinoxaline, via direct condensation with 1,2-phenylenediamine

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 2959, 1994 DOI: 10.1016/S0040-4039(00)76671-8

General Description

4,4′-Difluorobenzil is a benzil derivative. Its reaction with benzylurea and phenethylurea has been investigated. It is reported to undergo condensation with Fe2(SH)2(CO)6 to afford the adduct Fe2[S2C2(OH)2(C6H4-4-F)2](CO)6.

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