1,3,5-Tribromobenzene Chemical Properties

Melting point:

117-121 °C (lit.)

Boiling point:

271 °C (lit.)

Density 

2.3515 (estimate)

refractive index 

1.6340 (estimate)

Flash point:

271°C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in benzene, chloroform, and ether (Weast, 1986)

form 

Powder

color 

Almost white to orange-brown

Water Solubility 

Soluble in hot ethanol and acetic acid. Insoluble in water.

BRN 

1858917

InChIKey

YWDUZLFWHVQCHY-UHFFFAOYSA-N

CAS DataBase Reference

626-39-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1,3,5-tribromo-(626-39-1)

EPA Substance Registry System

1,3,5-Tribromobenzene (626-39-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-53

Safety Statements 

22-24/25-37/39-26

WGK Germany 

3

RTECS 

DC1957200

TSCA 

Yes

HS Code 

29036990

MSDS

• Language:English Provider:Tribromobenzene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,3,5-Tribromobenzene Usage And Synthesis

Chemical Properties

Lump powder; Vapour pressure of 1,3,5-tribromobenzene between 295 and 389 K (solid) and 397 and 410 K (liquid). The enthalpies of sublimation and vaporisation were derived from the relationship between vapour pressure and temperature: ΔH°SUB(334.78 K) = 83.54 ± 2 kJ/mol and ΔH°vap(403.23 K) = 58.68 ± 1.5 kJ/mol.

Uses

Intermediate in drug manufacturing; organic synthesis; internal standard in analysis of aqueous samples.

Uses

1,3,5-Tribromobenzene, is a reagent that can be used in the preparation of different inhibitors. It is also a substituted Bromobenzene, a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.

General Description

• 1,3,5-Tribromobenzene(TBB) acts as internal standard during derivatization step in determination of cyanide in human plasma and urine by gas chromatography-mass spectrometry.
• TBB forms molecular complexes of 1:2 stoichiometry with [60]-and [70] fullerenes.
• TBB reacts with perfluoroalkenylzinc reagent in the presence of Pd(Ph₃)₄ catalyst to yield a novel trifunctional monomer 1,3,5-tris(α, β, β-trifluorovinyl)benzene.

Environmental Fate

Photolytic. Peijnenburg et al. (1992) investigated the photodegradation of a variety of substituted aromatic halides using a Rayonet RPR-208 photoreactor equipped with 8 RUL 3,000- ? lamps (250–350 nm). The reaction of 1,3,5-tribromobenzene (initial concentration 10-5 M) was conducted in distilled water and maintained at 20 °C. Though no products were identified, the investigators reported photohydrolysis was the dominant transformation process. The measured pseudo-first-order reaction rate constant and corresponding half-life were 0.005/min and 140.5 min., respectively.
Chemical/Physical. 1,3,5-Tribromobenzene will not hydrolyze to any reasonable extent.

Purification Methods

Crystallise it from glacial acetic acid/water (4:1), then wash with chilled EtOH and dry in air. [Beilstein 5 H 213, 5 IV 685.]

1,3,5-Tribromobenzene(626-39-1)Related Product Information

• 2,4,6-Tribromophenol
• 2,4,6-TRIBROMORESORCINOL
• 2,4,6-TRIBROMOPHENYLTHIOUREA
• 3-METHYL-2,4,6-TRIBROMOANILINE
• 2,4,6-TRIBROMO-3-METHYLPHENOL
• HEXABROMOBENZENE
• Tribromobenzene
• 2,4,6-TRIBROMOTOLUENE
• 2-allyloxy-1,3,5-tribromobenzene
• 3-HYDROXY-2,4,6-TRIBROMOBENZALDEHYDE
• Pentabromophenol
• BISMUTH TRIBROMOPHENATE
• 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE
• 2,4,6-TRIBROMOBENZOIC ACID
• 2,4,6-Tribromoaniline
• 2,3,4,5,6-Pentabromoethylbenzene
• 3-Hydroxy-2,4,6-tribromobenzoic acid
• Decabromodiphenyl oxide