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phellopterin

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phellopterin Basic information

Product Name:
phellopterin
Synonyms:
  • phelloptorin
  • 4-Methoxy-9-(3-methyl-2-butenyloxy)-7H-furo[3,2-g][1]benzopyran-7-one
  • 4-methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
  • PHELLOPTERIN(P)
  • (5-Methoxy-8)-gama,gama-dimethylallyloxy(2',3',6,7-furanocoumarin)
  • NSC 152469
  • 4-Methoxy-9-prenyloxypsoralen
  • Phellopterin, 98%, from Changium smyrnioides Fedde ex H. Wolff
CAS:
2543-94-4
MF:
C17H16O5
MW:
300.31
Product Categories:
  • Miscellaneous Natural Products
Mol File:
2543-94-4.mol
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phellopterin Chemical Properties

Melting point:
102-103℃
Boiling point:
480.4±45.0 °C(Predicted)
Density 
1.243
storage temp. 
Store at -20°C
solubility 
Soluble in acetonitrile and chloroform
form 
powder
color 
Light yellow
LogP
2.867 (est)
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phellopterin Usage And Synthesis

Description

Phellopterin is a commonly used yin-nourishing medicine in clinical practice. Indications: Dryness of the lungs, dry cough, fever injury, thirst and other symptoms. It is found that the preparation methods of coralline mostly use organic reagent extraction and silica gel column separation.

Definition

ChEBI: Phellopterin is a member of psoralens.

Biological Activity

Phellopterin is a natural product isolated from P. trifoliata. It inhibits monocyte-endothelial cell adhesion by reducing TNF-alpha-induced VCAM-1 expression by regulating Akt and PKC pathways.

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