Pregna-1,4-diene-3,20-dione,11,17-dihydroxy-6-methyl-, (6a,11b)- Chemical Properties

Melting point:

222-231℃

Boiling point:

530.3±50.0 °C(Predicted)

Density 

1.21±0.1 g/cm3(Predicted)

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)

form 

Solid

pka

12.86±0.70(Predicted)

color 

White to Pale Beige

Stability:

Hygroscopic

Major Application

pharmaceutical (small molecule)

InChI

1S/C22H30O4/c1-12-9-15-16-6-8-22(26,13(2)23)21(16,4)11-18(25)19(15)20(3)7-5-14(24)10-17(12)20/h5,7,10,12,15-16,18-19,25-26H,6,8-9,11H2,1-4H3

InChIKey

UWMKPWKZGHRUQC-UHFFFAOYSA-N

SMILES

OC1(C2(C(C3C(C4(C(=CC(=O)C=C4)C(C3)C)C)C(C2)O)CC1)C)C(=O)C

Safety Information

WGK Germany 

WGK 3

HS Code 

2937220000

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 4 Oral
Repr. 1B

Pregna-1,4-diene-3,20-dione,11,17-dihydroxy-6-methyl-, (6a,11b)- Usage And Synthesis

Uses

Deltamedrane is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.

Pregna-1,4-diene-3,20-dione,11,17-dihydroxy-6-methyl-, (6a,11b)-(6870-94-6)Related Product Information

• Fluorometholone
• 1β-Hydroxy-6α-Methyl-1,4-androstadiene-3,17-dione
• Methylprednisolone EP Impurity E
• Prednisolone
• 6-methylprednisone
• Methylprednisolone acetate
• (6α)-17,21-Dihydroxy-6-Methylpregna-1,4,9(11)-triene-3,20-dione
• Prednisolone succinate
• (6α,11β)-11,20-Dihydroxy-6-Methyl-3-oxopregna-1,4,17(20)-trien-21-al
• 11-beta,17-alpha,21-trihydroxy-6-alpha-methylpregn-4-ene-3,20-dione
• 6β-Methylprednisolone
• Methylprednisolone
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-chloro-11,17-dihydroxy-16-methyl-, (11β,16β)-
• Pregna-1,4-diene-3,20-dione,11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide 21-acetate
• Pregna-4,6-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6β,11β,16α)-
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-[ethylidenebis(oxy)]-6,9-difluoro-11-hydroxy-, [6α,11β,16α(S)]- (9CI)
• Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[propylidenebis(oxy)]-, [11β,16α(R)]- (9CI)