Basic information Safety Supplier Related

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole

Basic information Safety Supplier Related

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Basic information

Product Name:
1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
Synonyms:
  • 1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
  • (1H-1,2,4-triazol-1-yl)methyl>
  • (2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-<
  • Efinaconazole Impurity 18
  • Efinaconazole Related Impurity 4
  • (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
  • 1H-1,2,4-Triazole, 1-[[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI)
  • (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol...
CAS:
135270-07-4
MF:
C12H11F2N3O
MW:
251.23
Mol File:
135270-07-4.mol
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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Chemical Properties

Boiling point:
371.6±52.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
pka
2.75±0.10(Predicted)
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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Usage And Synthesis

Uses

(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of ent-Efinaconazole (E435075); the S,S-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazoleSupplier

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