1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole CAS#: 135270-07-4

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Basic information

Product Name:

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole

Synonyms:

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
(1H-1,2,4-triazol-1-yl)methyl>
(2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-<
Efinaconazole Impurity 18
Efinaconazole Related Impurity 4
(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
1H-1,2,4-Triazole, 1-[[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI)
(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol...

CAS:

135270-07-4

MF:

C12H11F2N3O

MW:

251.23

Mol File:

135270-07-4.mol

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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Chemical Properties

Boiling point:: 371.6±52.0 °C(Predicted)
Density: 1.41±0.1 g/cm3(Predicted)
pka: 2.75±0.10(Predicted)

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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Usage And Synthesis

Uses

(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of ent-Efinaconazole (E435075); the S,S-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazoleSupplier

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