4-(N-Maleimido)benzophenone
4-(N-Maleimido)benzophenone Basic information
- Product Name:
- 4-(N-Maleimido)benzophenone
- Synonyms:
-
- 4-(N-MALEIMIDO)BENZOPHENONE
- 4-(MALEIMIDO)BENZOPHENONE
- AKOS MSC-0079
- BENZOPHENONE-4-MALEIMIDE
- 1-(4-benzoylphenyl)pyrrole-2,5-dione
- N-(4-benzoylphenyl)maleimide
- 4-(Maleinimido)benzophenone
- 1-(4-BENZOYLPHENYL)-1H-PYRROLE-2,5-DIONE
- CAS:
- 92944-71-3
- MF:
- C17H11NO3
- MW:
- 277.27
- Product Categories:
-
- Maleimide Derivatives
- Cross Linking Reagents
- MTS & Sulfhydryl Active Reagents
- Linking Reagents
- Aromatics
- Heterocycles
- Heterobifunctional Cross-Linking Reagents
- Protein Modification
- Protein Structural Analysis
- Building Blocks
- Carbonyl Compounds
- Chemical Synthesis
- Crosslinking
- Cyclic Imides
- Organic Building Blocks
- Proteomics
- Mol File:
- 92944-71-3.mol
4-(N-Maleimido)benzophenone Chemical Properties
- Melting point:
- 155-157°C
- Boiling point:
- 472.9±28.0 °C(Predicted)
- Density
- 1.330±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- chloroform: 50 mg/mL
- form
- Solid
- pka
- -3.80±0.20(Predicted)
- color
- Light Beige
MSDS
- Language:English Provider:SigmaAldrich
4-(N-Maleimido)benzophenone Usage And Synthesis
Chemical Properties
Light Beige Solid
Uses
Maleimide-containing benzophenone as photoinitiator
Uses
A heterobifunctional cross-linking reagent containing a sulfhydryl-specific group and a photo-active group. Typically, coupled initially by thioether to molecule containing free sulfhydryl buffered at pH 6.8 (6.5-7.0). Second bonding occurs during UV irradiation (250 nm) via diradical excited state. Benzophenones demonstrate greater specificity for C-H insertion and are more stable in water than analogous reagents. In general they are more efficient in attachment because they may be repeatedly irradiated; however, a more intense irradiation may be required. The benzophenone is not sensitive to
Uses
4-(N-Maleimido)benzophenone can be used as a sulfhydryl reactive heterobifunctional photocrosslinking reagent. It generates photoactivatable conjugates from thiols
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4-(N-Maleimido)benzophenone(92944-71-3)Related Product Information
- 4-(MALEINIMIDO)PHENYL ISOCYANATE*
- 2-Maleimido acetic acid
- DISUCCINIMIDYL SEBACATE
- 4-Maleimidobenzoic acid
- DISUCCINIMIDYL SUBERATE
- N-Succinimidyl maleimidoacetate
- Suberate Bis(sulfosuccinimidyl) Sodium Salt
- 4-(DIETHYLAMINO)BENZOPHENONE
- 1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE
- 4'-DIMETHYLAMINOACETOPHENONE
- 4-Diethylaminobenzaldehyde
- 4-(Dimethylamino)benzophenone
- 4'-DIETHYLAMINOACETOPHENONE
- 4'-ACETAMIDOACETOPHENONE
- N-(4-ETHYLPHENYL)MALEIMIDE
- 4-(N-Maleimido)benzophenone
- N-(4-ACETYLPHENYL)MALEIMIDE
- N-(4-benzoylphenyl)acetamide