Basic information Safety Supplier Related

4-(N-Maleimido)benzophenone

Basic information Safety Supplier Related

4-(N-Maleimido)benzophenone Basic information

Product Name:
4-(N-Maleimido)benzophenone
Synonyms:
  • 4-(N-MALEIMIDO)BENZOPHENONE
  • 4-(MALEIMIDO)BENZOPHENONE
  • AKOS MSC-0079
  • BENZOPHENONE-4-MALEIMIDE
  • 1-(4-benzoylphenyl)pyrrole-2,5-dione
  • N-(4-benzoylphenyl)maleimide
  • 4-(Maleinimido)benzophenone
  • 1-(4-BENZOYLPHENYL)-1H-PYRROLE-2,5-DIONE
CAS:
92944-71-3
MF:
C17H11NO3
MW:
277.27
Product Categories:
  • Maleimide Derivatives
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents
  • Linking Reagents
  • Aromatics
  • Heterocycles
  • Heterobifunctional Cross-Linking Reagents
  • Protein Modification
  • Protein Structural Analysis
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Crosslinking
  • Cyclic Imides
  • Organic Building Blocks
  • Proteomics
Mol File:
92944-71-3.mol
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4-(N-Maleimido)benzophenone Chemical Properties

Melting point:
155-157°C
Boiling point:
472.9±28.0 °C(Predicted)
Density 
1.330±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
chloroform: 50 mg/mL
form 
Solid
pka
-3.80±0.20(Predicted)
color 
Light Beige
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29251900

MSDS

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4-(N-Maleimido)benzophenone Usage And Synthesis

Chemical Properties

Light Beige Solid

Uses

Maleimide-containing benzophenone as photoinitiator

Uses

A heterobifunctional cross-linking reagent containing a sulfhydryl-specific group and a photo-active group. Typically, coupled initially by thioether to molecule containing free sulfhydryl buffered at pH 6.8 (6.5-7.0). Second bonding occurs during UV irradiation (250 nm) via diradical excited state. Benzophenones demonstrate greater specificity for C-H insertion and are more stable in water than analogous reagents. In general they are more efficient in attachment because they may be repeatedly irradiated; however, a more intense irradiation may be required. The benzophenone is not sensitive to

Uses

4-(N-Maleimido)benzophenone can be used as a sulfhydryl reactive heterobifunctional photocrosslinking reagent. It generates photoactivatable conjugates from thiols

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