3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)-
3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- Basic information
- Product Name:
- 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)-
- Synonyms:
-
- Tofacitinib-3
- 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)-
- Tofacitinib impurity 2/(3S,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
- (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-aminehydrochloride
- Azilsartan medoxomil impurity349
- Tofacitinib Impurity 03
- Tofatinib Impurity 34（HCI)
- Non-corresponding isomer impurity 1
- CAS:
- 1821769-41-8
- MF:
- C14H23ClN2
- MW:
- 254.8
- Mol File:
- 1821769-41-8.mol
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3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- Chemical Properties
- InChI
- InChI=1/C14H22N2.ClH/c1-12-8-9-16(11-14(12)15-2)10-13-6-4-3-5-7-13;/h3-7,12,14-15H,8-11H2,1-2H3;1H/t12-,14-;/s3
- InChIKey
- FVRZQLQXDPJADE-JAUJFHBUNA-N
- SMILES
- C(C1C=CC=CC=1)N1CC[C@@H](C)[C@H](NC)C1.Cl |&1:10,12,r|
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3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)- Usage And Synthesis
Uses
(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride is the hydrochloride salt of (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine (B276220) which is an intermediate in the synthesis of (3S,4R)-Tofacitinib (T528010). (3S,4R)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)-Supplier
Hubei Yangxin Medical Technology Co., Ltd. Gold
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- 15374522761
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Daicel Chiral Technologies (China)CO.,LTD
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- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
S.Z. PhyStandard Bio-Tech. Co., Ltd.
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- 0755-4000505016 13380397412
- 3001272453@qq.com
Nantong MYBio-pharm. Co., Ltd.
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- 0513-85921823 18662920231
- sales@ntminyanmedical.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
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- 0510-85629785 18013409632
- sales@reading-chemicals.com
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3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)-(1821769-41-8)Related Product Information
- Benzyl chloride
- Tofacitinib
- (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
- CYANOACETIC ACID-OSU
- N-Hydroxysuccinimide
- N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
- 3-Piperidinamine,4-methyl-1-(phenylmethyl)-,(3R,4R)-rel-
- methyl3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin -4-yl)amino)piperidin-1-yl)-3-oxopropanoate
- (3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
- Tofacitinib impurity 1
- Tofacitinib Impurity 6
- 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
- N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 3-((3R,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanaMide
- 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
- 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyriMidin-4-yl)(Methyl)aMino)-4-Methylpiperidin-1-yl)-3-oxopropanenitrile
- 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
- Tofacitinib Impurity 2