2-Amino-4,6-dichlorotriazine Chemical Properties

Melting point:

239-242°C

Boiling point:

428.8±28.0 °C(Predicted)

Density 

1.731±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO, Methanol (Sparingly)

form 

Solid

pka

2.28±0.10(Predicted)

color 

White to Off-White

BRN 

124266

Stability:

Stable at RT

InChI

InChI=1S/C3H2Cl2N4/c4-1-7-2(5)9-3(6)8-1/h(H2,6,7,8,9)

InChIKey

MCLXKFUCPVGZEN-UHFFFAOYSA-N

SMILES

N1=C(Cl)N=C(Cl)N=C1N

CAS DataBase Reference

933-20-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38-22

Safety Statements 

23-36/37/39-26

WGK Germany 

3

RTECS 

XY3177000

HazardClass 

IRRITANT

HS Code 

2933698090

2-Amino-4,6-dichlorotriazine Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

An aromatic intermediate compound, 2-Amino-4,6-dichlorotriazine can be useful for the preparation of substituted melamine, ammelides, and ammelines.

Synthesis

General procedure for the synthesis of 2-amino-4,6-dichloro-S-triazine from cyanuric chloride: an equimolar amount of ammonium hydroxide solution was added dropwise to an anhydrous dichloromethane (10 mL) solution of cyanuric chloride (2.16 g, 11.69 mmol) under stirring conditions. Upon completion of the reaction, the reaction mixture was purified by fast column chromatography (eluent: ethyl acetate/dichloromethane, 8:2, v/v) to afford the target compound 2-amino-4,6-dichloro-S-triazine (I) in 99% yield.

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 11, p. 2519 - 2529
[2] Bioorganic Chemistry, 2019, vol. 82, p. 117 - 122
[3] Journal of Organic Chemistry, 2016, vol. 81, # 10, p. 4066 - 4075
[4] Journal of the American Chemical Society, 1994, vol. 116, # 6, p. 2382 - 2391
[5] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994, vol. 33, # 8, p. 759 - 760

2-Amino-4,6-dichlorotriazine(933-20-0)Related Product Information

• 3-Aminobenzotrifluoride
• Diethylaminosulfur trifluoride
• ALTRENOGEST
• Lithium bis(trimethylsilyl)amide
• Glycine
• Betaine
• 1,3,5-Triazine
• 2-(Trifluoromethoxy)aniline
• Tris(hydroxymethyl)aminomethane
• ANILAZINE
• REACTIVE ORANGE 14
• 4,6-Dichloro-N-(4-fluorophenyl)-1,3,5-triazin-2-amine
• REACTIVE BLUE 4
• PROCION RED MX-5B
• 2,4-Dichloro-1,3,5-triazine
• 4,6-dichloro-N-(3-(trifluoromethyl)phenyl)-1,3,5-
• 2-(3-CARBOXYANILINO)-4,6-DICHLORO-1,3,5-TRIAZINE
• 2-(N,N-DIETHYLAMINO)-4,6-DICHLOROTRIAZINE