ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Borate > 4-Pyrazoleboronic acid pinacol ester
4-Pyrazoleboronic acid pinacol ester
4-Pyrazoleboronic acid pinacol ester Basic information
- Product Name:
- 4-Pyrazoleboronic acid pinacol ester
- Synonyms:
-
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole,min.97%
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, min. 97%
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole4-Pyrazoleboronic acid pinacol ester
- 4-Pyrazoleboronic acid pinacol ester,97%
- 4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyrazole
- 4-Pyrazoleboronic acid pinaol ester
- 1H-Pyrazole, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
- 4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
- CAS:
- 269410-08-4
- MF:
- C9H15BN2O2
- MW:
- 194.04
- EINECS:
- 629-131-7
- Product Categories:
-
- organic or inorganic borate
- Pyrazole series
- API intermediates
- Boronic acid
- OLED materials,pharm chemical,electronic
- 269410-08-4
- Mol File:
- 269410-08-4.mol
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4-Pyrazoleboronic acid pinacol ester Chemical Properties
- Melting point:
- 142-146 °C (lit.)
- Boiling point:
- 335.4±15.0 °C(Predicted)
- Density
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO, Ethyl Acetate, Methanol
- pka
- 13.36±0.50(Predicted)
- form
- Powder
- color
- Off-white to tan
- Water Solubility
- insoluble
- InChIKey
- TVOJIBGZFYMWDT-UHFFFAOYSA-N
- CAS DataBase Reference
- 269410-08-4(CAS DataBase Reference)
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MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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4-Pyrazoleboronic acid pinacol ester Usage And Synthesis
Chemical Properties
Off-white to tan powder
Uses
4-Pyrazoleboronic Acid Pinacol Ester is used in the preparation of Rho kinase (ROCK) inhibitors as wella s other biologically active compounds.
Uses
1H-Pyrazole-4-boronic acid pinacol ester is a useful reagent for Suzuki-Miyaura cross-couplings as well as Ruthenium-catalyzed asymmetric hydrogenation. It is also used as reagent for preparing VEGF, Aurora, RHO (ROCK), Janus Kinase 2, c-MET, ALK, S-nitrsoflutathione reductase, CDC7, Acetyl-CoA carboxylase inhibitors as well as other biologically active compounds.
Uses
Reagent used for
- Suzuki-Miyaura cross-couplings
- Ruthenium-catalyzed asymmetric hydrogenation
Reagent used in preparation of inhibitors of many highly significant therapeutic enzymes and kinases containing the privileged scaffold pyrazole, including
- VEGF
- Aurora
- Rho (ROCK)
- Janus Kinase 2 (JAK)
- c-MET
- ALK
- S-nitrosoglutathione reductase
- CDC7
- Acetyl-CoA carboxylase
- Prosurvival Bcl-2 protein
- Viral RNA-Dependent RNA polymerase
- Long Chain Fatty Acid Elongase 6
- PI3
- AKT
- Chk1
- Protein Kinase B
4-Pyrazoleboronic acid pinacol esterSupplier
AllyChem Co., Ltd. Gold
- Tel
- 0411-62313318 13942603642
- info@allychem.com
Shanghai Arbor Chemical Co., Ltd. Gold
- Tel
- 021-60451682 15021268886
- sales@arborchemical.com
Aikon International Limited Gold
- Tel
- 025-58859352 18068836627
- sales01@aikonchem.com
Hangzhou Chemtrue Bio-Tech Co.,Ltd. Gold
- Tel
- 0571-86828652 18857119830
- sales@chemtrue-bio.com
Suzhou You Boron Photoelectric Material Co., Ltd. Gold
- Tel
- 15301358979
- 37303017@qq.com
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4-Pyrazoleboronic acid pinacol ester(269410-08-4)Related Product Information
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- 1-Methyl-4-pyrazole boronic acid pinacol ester