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ISOBARBITURIC ACID

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ISOBARBITURIC ACID Basic information

Product Name:
ISOBARBITURIC ACID
Synonyms:
  • Fluorouracil Impurity 2(Fluorouracil EP Impurity B)
  • Fluorouracil EP Impurity B
  • dihydropyrimidine-2,4,5(3H)-trione
  • TRIFLUOROACETIC ACID REAGENTPLUS 99%
  • 2,4,5(3H)-Pyrimidinetrione, dihydro- (9CI)
  • 2,4,5-Trihydroxypyrimidine, 5-Hydroxyuracil
  • 1,6-Dihydro-2,4,5(3H)-pyrimidinetrione
  • 2-Hydroxy-1,6-dihydropyrimidine-4,5-dione
CAS:
496-76-4
MF:
C4H4N2O3
MW:
128.09
EINECS:
207-829-9
Product Categories:
  • Nucleotides
  • Aromatic
  • Bases & Related Reagents
  • Heterocycles
  • APIs & Intermediate
  • PYRIMIDINE
Mol File:
496-76-4.mol
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ISOBARBITURIC ACID Chemical Properties

Melting point:
>300 °C (dec.)(lit.)
Density 
1.455±0.06 g/cm3(Predicted)
solubility 
Soluble in DMSO (Sparingly), Methanol (Sparingly).
pka
8.25±0.20(Predicted)
form 
crystalline
color 
light yellow
BRN 
127205
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2933599550
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ISOBARBITURIC ACID Usage And Synthesis

Chemical Properties

light yellow to beige granular powder

Uses

A 5-hydroxy derivative of the nucleobase Uracil (U801000) and an isomer of Barbituric Acid (B118650). Studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been u sed as oxidative DNA damage biomarker in tissue engineered skin

Uses

2,4,5-Trihydroxypyrimidine studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin. It acts as an antagonist of uracil in the growth of Lactobacillus casei.

ISOBARBITURIC ACIDSupplier

J & K SCIENTIFIC LTD.
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Alfa Aesar
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Energy Chemical
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