DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE Chemical Properties

Boiling point:

146-149 °C14 mm Hg(lit.)

Density 

1.052 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.430(lit.)

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

Chloroform, Dichloromethane

form 

Oil

color 

Colourless

Water Solubility 

Soluble in chloroform and dichloromethane. Not miscible or difficult to mix in water.

Sensitive 

Moisture Sensitive

BRN 

1785614

InChI

1S/C10H23O5P/c1-5-12-10(13-6-2)9-16(11,14-7-3)15-8-4/h10H,5-9H2,1-4H3

InChIKey

LUQYELQXRPNKRY-UHFFFAOYSA-N

SMILES

CCOC(CP(=O)(OCC)OCC)OCC

CAS DataBase Reference

7598-61-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

RIDADR 

UN2810

WGK Germany 

3

F 

21

HazardClass 

6.1

HS Code 

29319090

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE Usage And Synthesis

Chemical Properties

Colourless Oil

Uses

Diethyl 2,2-diethoxyethylphosphonate is used reactant for synthesis of α,β-alkenal derivatives by two-carbon homologation, lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions, α-Phosphovinyl radicals via a radical trapping sequence, inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions and for Friedel-Crafts reactions.

Uses

Reactant for synthesis of:

• α,β-Alkenal derivatives by two-carbon homologation
• Lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions
• α-Phosphovinyl radicals via a radical trapping sequence
• Inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions

Uses

Diethyl 2,2-diethoxyethylphosphonate can be used as a useful wittig reagent.

reaction suitability

reaction type: C-C Bond Formation

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE(7598-61-0)Related Product Information

• Diethyl methylphosphonate
• Dimethyl methylphosphonate
• DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
• DIMETHYL ETHYLPHOSPHONATE
• Dimethyl 2-hydroxyethylphosphonate
• DIMETHYL ETHYLPHOSPHONITE
• DIETHYL 2,2-DIMETHOXYETHYLPHOSPHONATE
• DIETHYL ETHYLPHOSPHONATE
• ETHYL METHYLPHOSPHONIC ACID
• ETHYLPHOSPHONIC ACID
• METHYLPHOSPHONIC ACID
• Methyldiethoxyphosphine
• DIETHYL PHOSPHATE
• ETHYL METHYLPHOSPHINATE
• METHYL METHYLPHOSPHONIC ACID
• ETHYL HYDROGEN ETHYLPHOSPHONATE
• 2-HYDROXYETHYL PHOSPHONIC ACID
• DIETHYL ETHYLPHOSPHONITE